Colchicine Therapy for Psoriasis

April 1976 in “ Archives of Dermatology ”

P.M. Gaylarde

telogen effluvium hair shedding telogen ratio chorionic gonadotropin colchicine psoriasis skin necrosis Goeckerman regimen hCG hair loss topical colchicine

TLDR Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.

The document reported a case of telogen effluvium in a 36-year-old woman who lost approximately 14.5 kg rapidly through a starvation diet and chorionic gonadotropin injections, leading to significant hair shedding and a 38% telogen ratio, supporting the idea that sudden weight loss can cause this type of hair loss. Additionally, it included a letter cautioning against the use of topical colchicine for psoriasis treatment due to observed skin necrosis and systemic effects in guinea pigs, calling for thorough safety testing before its human application. Other topics mentioned were the lack of evidence linking Toxoplasma gondii to pityriasis lichenoides in the central United States and a modified Goeckerman regimen for psoriasis.

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research Colchicine Therapy for Psoriasis

1 citations, April 1976 in “Archives of Dermatology”

Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.