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Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

Excess vitamin A causes lasting gland changes in mouse hair follicles.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Deleting NIPP1 in mouse skin cells causes early aging and chronic skin issues.

Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

Stem cells can rejuvenate skin, restore hair, and aid in wound healing.

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Melanocytes are cells that make skin and hair color and help protect skin from sun damage.

Certain astrocytes can protect the brain and improve recovery after a stroke, and a hair loss drug might reduce cancer spread.

Special astroglia cells improved stroke recovery in rats, a hair growth drug reduced cancer spread, and tiny magnesium structures were more easily shaped.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.

Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.

The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.

The document concludes that the technique allows for the detection of LDH activity in various tissues, showing where cells are actively metabolizing glucose.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

The research maps the complex development of early mouse skin, identifying diverse cell types and their roles in forming skin layers and structures.

Skin patterns form through molecular signals and genetic factors, affecting healing and dermatology.

NGAL indicates abnormal skin cell differentiation.