research Effect of Allopregnanolone and Allotetrahydrodeoxycorticosterone on Spike-Wave Discharges in the EEG of Absence Epilepsy Rat Models
The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.
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research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research Preparation of Mohs Micrographic Surgery Frozen Sections: Three New Pearls Leading to a Simplified, More Effective Process
Three new techniques simplify and improve the preparation of tissue samples for skin cancer surgery.
research Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy
A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.
research The Influence of 3% Hydrogen Peroxide on the Survival Rate of Hair Grafts When Used as an Antiseptic Solution for Surgical Wound Care
3% hydrogen peroxide does not harm hair graft survival compared to saline.
research Issues in the Treatment of Epilepsy
Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.
research Hair Removal Using the Long-Pulsed Ruby Laser
Long-pulsed ruby lasers effectively reduce hair for up to 2 years with minimal pain.
research Comparison of 5% Minoxidil Lotion Monotherapy Versus Its Combination with Autologous Platelet-Rich Plasma in Androgenetic Alopecia in One Hundred Males
Combination therapy promotes better hair growth and density.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research The Use of Phosphodiesterase Inhibitors for the Treatment of Alopecia
Caffeine shows promise for treating some types of hair loss, but more research is needed.
research Automatic Artificial Hair Implant: Safety and Efficacy in Androgenetic Alopecia. A Prospective Study with a Highly Biocompatible Fiber
Implant safely and effectively treats hair loss.
research Dermoscopic Evaluation of Therapeutic Response to Intralesional Triamcinolone Acetonide in the Treatment of Alopecia Areata
Intralesional triamcinolone acetonide effectively treats alopecia areata, as shown by significant improvements in hair regrowth and dermoscopic indicators.
research Efficacy and Safety of a Food Supplement Containing L-Cystine, Serenoa Repens Extract, and Biotin for Hair Loss in Healthy Males and Females: A Prospective, Randomized, Double-Blinded, Controlled Clinical Trial
The food supplement with L-cystine, Serenoa repens extract, and biotin safely reduced hair loss and improved hair growth in men and women.
research Minoxidil Improved Hair Density in an Asian Girl with Short Anagen Syndrome: A Case Report and Review of Literature
Minoxidil treatment increased hair density in a young Asian girl with short anagen syndrome, but didn't improve hair length or thickness.
research An Open-Label Pilot Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
research Hot Water Extract of Oriental Melon Leaf Promotes Hair Growth and Prolongs Anagen Hair Cycle: In Vivo and In Vitro Evaluation
Oriental melon leaf extract may help hair grow and keep it in the growing phase longer.
research Women's Health Considerations for Lipid Management
Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.
research Topical Products for Human Hair Regeneration: A Comparative Study on an Animal Model
Minoxidil was the most effective treatment for hair regrowth in rats compared to Aminexil or Kerium.
research Managing Menopause Chapter 8: Sexuality and Menopause
Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
research Clinical and Histological Characterization of Multifocal, Spontaneous, Noninfectious Alopecia in Norwegian Puffin Dogs (Lundehunds)
Norwegian puffin dogs have a unique type of hair loss that often doesn't get better on its own and responds well to ciclosporin treatment.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Hair Loss in Hospital Medicine: A Practical Guide
The guide helps clinicians diagnose and manage hair loss, detailing examination techniques and treatments for different types of alopecia.
research Mesotherapy: Myth and Reality
Mesotherapy lacks strong evidence for effectiveness and safety, and its ingredients are not FDA-approved for subcutaneous use.
research Impact of Hormones on Female Sexual Function and Dysfunction
Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.
research Simvastatin-Induced Myoglobinuric Acute Kidney Injury Following Ciclosporin Treatment for Alopecia Universalis
Combining ciclosporin and simvastatin can cause severe kidney damage.
research Hirsutism: From Brazil to a Place Near You
No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
research Green Tea Extract: A Novel Addition to the Antihirsutism Armamentarium?
Green tea extract may help reduce excessive hair growth.
research Menopause
The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
research Implantation of Biocompatible Fibers for the Temporary Correction of Scalp Scars and Androgenetic Alopecia
Fiber implants effectively treat permanent hair loss with over 85% success and minimal complications.