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    Glossary EDARADD gene

    gene involved in hair, teeth, and sweat gland development

    The EDARADD gene provides instructions for making a protein that interacts with the EDAR protein, which is crucial for the development of hair, teeth, and sweat glands. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which affects the normal development of these structures.

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    Research 30 of 86

    1. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    2. Novel missense mutation in the EDA gene in a family affected by oligodontia 2016 · 12 citations
    3. Advances in the genetic understanding of hypohidrotic ectodermal dysplasia Expert opinion on orphan drugs · 2017 · 1 citations
    4. Current Genetics in Hair Diseases InTech eBooks · 2013 · 1 citations
    5. Genetics of Alopecia Encyclopedia of Life Sciences · 2012
    6. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    7. Mutational spectrum in 101 patients with hypohidrotic ectodermal dysplasia and breakpoint mapping in independent cases of rare genomic rearrangements Journal of Human Genetics · 2016 · 30 citations
    8. Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation The EMBO Journal · 2016 · 29 citations
    9. Inherited Disorders of the Hair Elsevier eBooks · 2013 · 2 citations
    10. Interplay between EDA-EDAR and WNT signalling pathways in the development of skin appendages in hypohidrotic ectodermal dysplasia Pediatria i Medycyna Rodzinna · 2025 · 1 citations
    11. To grow or not to grow: Hair morphogenesis and human genetic hair disorders Seminars in Cell & Developmental Biology · 2013 · 43 citations
    12. Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen Nature Communications · 2014 · 50 citations
    13. A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1 Journal of Medical Genetics · 2012 · 17 citations
    14. Hair shaft structures in EDAR induced ectodermal dysplasia BMC Medical Genetics · 2015 · 5 citations
    15. A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features Nature Communications · 2016 · 196 citations
    16. Molecular basis of hypohidrotic ectodermal dysplasia: an update Journal of Applied Genetics · 2015 · 85 citations
    17. Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats Animals · 2023 · 1 citations
    18. <i>WNT10A</i> , dermatology and dentistry British Journal of Dermatology · 2021 · 30 citations
    19. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    20. Regeneration of skin appendages and nerves: current status and further challenges Journal of Translational Medicine · 2020 · 71 citations
    21. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    22. Genetic Hair Disorders: A Review Dermatology and Therapy · 2019 · 26 citations
    23. Rhamnose-mediated modulation of hair follicle growth: insights from chemical genomics bioRxiv (Cold Spring Harbor Laboratory) · 2025
    24. Fondation René Touraine Experimental Dermatology · 2013
    25. Molecular Mechanisms Affecting Development of Animal Fibers and Some Studies on Goats Livestock studies · 2023
    26. Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle BMC ecology and evolution · 2023 · 2 citations
    27. Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis Frontiers in oncology · 2022 · 13 citations
    28. Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen) ˜The œAmerican journal of pathology · 2006 · 43 citations
    29. Cutaneous, Cranial, and Skeletal Defects in Children and Adults with Focal Dermal Hypoplasia Children · 2023 · 4 citations
    30. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution 2007 · 170 citations