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      SOX2 in the Skin: Roles in Biology and Pathology

      research SOX2 in the Skin

      1 citations , September 2015 in “Elsevier eBooks”
      This review discusses the role of Sox2 in skin development, hair follicle regeneration, cancer, and wound healing, and reports no new experimental results.
      Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis

      research Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis

      March 2026 in “Calcified Tissue International”
      This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.
      Resident Stem Cells in Skin

      research Resident Stem Cell in Skin

      1 citations , October 2012 in “Elsevier eBooks”
      This article reviews advancements in understanding skin regeneration and suggests that bioengineering skin surrogates may soon enhance treatments for skin trauma, but it presents no new clinical findings.
      High Proliferation and Delamination During Skin Epidermal Stratification

      research High proliferation and delamination during skin epidermal stratification

      51 citations , May 2021 in “Nature Communications”
      This study found that ablating centrosomes in developing epidermis alters keratinocyte division without majorly affecting differentiation, suggesting early epidermal development is driven by high proliferation and cell delamination.
      Cutaneous Tumors of Pilar Origin with Associated Syndromes

      research Cutaneous Tumours of Pilar Origin with Associated Syndromes

      October 2023 in “Research Review”
      This source describes the development, structure, and types of skin appendage tumors, noting both benign and malignant forms, potential associations with syndromes, and categories based on follicular differentiation.
      More Than One Way to Skin

      research More than one way to skin . . .

      218 citations , April 2008 in “Genes & Development”
      This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.
      Stem Cells Behind the Barrier: Mechanisms Regulating Epidermal Stem and Progenitor Cell Differentiation

      research Stem Cells behind the Barrier

      22 citations , June 2013 in “International journal of molecular sciences”
      This review discusses the mechanisms governing epidermal stem and progenitor cell differentiation, emphasizing the balance necessary for maintaining skin barrier function, and reports no new experimental findings.
      The Hair Follicle as a Dynamic Mini-Organ

      research The Hair Follicle as a Dynamic Miniorgan

      759 citations , February 2009 in “Current Biology”
      This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.
      Wnt Signaling in Skin Development, Homeostasis, and Disease

      research Wnt Signaling in Skin Development, Homeostasis, and Disease

      260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
      Hormone Replacement Therapy and the Skin

      research Hormone replacement therapy and the skin

      138 citations , May 2000 in “Maturitas”
      This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.
      Keratin 17 Null Mice Exhibit Age- And Strain-Dependent Alopecia

      research Keratin 17 null mice exhibit age- and strain-dependent alopecia

      122 citations , June 2002 in “Genes & Development”
      This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.
      Genetic Basis of Skin Appendage Development

      research Genetic basis of skin appendage development

      111 citations , January 2007 in “Seminars in cell & developmental biology”
      This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.
      Molecular Signaling in Feather Morphogenesis

      research Molecular signaling in feather morphogenesis

      85 citations , October 2006 in “Current opinion in cell biology”
      This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
      The Genetics of Hair Shaft Disorders

      research The genetics of hair shaft disorders

      59 citations , June 2008 in “Journal of The American Academy of Dermatology”
      This article reviews major types of genetic hair shaft defects and associated syndromes, emphasizing understanding histologic features and diagnostic methods, but reports no new clinical findings.
      Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

      research Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

      55 citations , October 1992 in “Archives of Dermatology”
      In this study, researchers observed that loose anagen hair syndrome is an autosomal dominant disorder characterized by abnormal hair follicle structure and premature keratinization, possibly due to signaling and desmosomal component disturbances.
      Hair Shaft Abnormalities: Clues to Diagnosis and Treatment

      research Hair Shaft Abnormalities – Clues to Diagnosis and Treatment

      44 citations , January 2005 in “Dermatology”
      This article reviews the clinical and diagnostic features of hair shaft disorders, emphasizing the role of structured patient assessments and the avoidance of hair trauma, but reports no new results.
      Congenital Hair Loss Disorders: Rare, But Not Too Rare

      research Congenital hair loss disorders: Rare, but not too rare

      41 citations , November 2011 in “The Journal of Dermatology”
      This review identifies genetic mutations associated with congenital hair loss disorders in Japanese populations, particularly highlighting common LIPH gene mutations linked to woolly hair/hypotrichosis, and reports no new clinical results.