1 citations
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October 2023 in “International journal of Ayurveda and pharma research” This source reviews various herbal remedies for treating hair loss, highlighting their potential benefits and reduced side effects compared to synthetic treatments, which often do not deliver lasting results and can cause adverse reactions.
April 2026 in “International Journal of Allied Medical Sciences and Clinical Research” In this study, researchers formulated an herbal hair serum with plant extracts like Hibiscus and Nigella and observed that it demonstrated acceptable physical properties and potential anti-dandruff activity, proposing it as a safe and effective alternative to synthetic hair care products.
July 2025 in “Pharmaceutical Sciences & Analytical Research Journal” This overview discusses the impact of alopecia on quality of life and finds that while various factors can cause hair loss, herbal therapies offer promising, accessible, and low-cost complementary treatment options, although further clinical validation is needed.
June 2025 in “INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT” This study assessed a herbal dry shampoo comprising natural ingredients like Shikakai and Reetha, finding it effectively passed physicochemical tests but highlighted the need for more research to optimize product quality and safety.
This review article underscores the benefits of herbal hair oil formulations, which include ingredients like Bhringraj leaves and coconut oil, in promoting hair health with fewer side effects compared to chemical products, offering nutrients for sebaceous gland function.
This review discusses how herbal therapies may help manage alopecia and improve quality of life, noting their potential benefits like lower cost and fewer side effects, but emphasizes that more clinical studies are needed for validation.
December 2024 in “Journal of Population Therapeutics and Clinical Pharmacology” This review highlights the potential benefits of using rosemary and kalonji seeds for hair health, focusing on their phytochemical properties, mechanisms of action, and therapeutic potential in treating conditions such as alopecia and dandruff.
July 2023 in “International journal of current research in chemistry and pharmaceutical sciences” In this study, researchers formulated a herbal shampoo using traditional ayurvedic herbs and reported that it may serve as a natural and effective alternative to synthetic shampoos for cleaning and managing hair, emphasizing the growing preference for herbal products over chemical ones.
January 2016 in “Springer eBooks” The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
234 citations
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April 2000 in “Gene” This review discusses the expression patterns and biochemical roles of Msx and Dlx genes during development but does not present new research findings.
179 citations
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July 2016 in “Nature Reviews Molecular Cell Biology” This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.
83 citations
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May 2013 in “International Journal of Molecular Sciences” This review explores embryonic epidermal development and discusses key molecular regulators and roles of the sub-epidermal mesenchyme, but reports no new experimental results.
23 citations
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December 2020 in “Frontiers in Cell and Developmental Biology” This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.
16 citations
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March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers observed that a noncanonical mechanism involving the γ-secretase-dependent, RBPj-independent Notch intracellular domain improves survival in Msx2-Cre mice by delaying hair follicle destruction and reducing disease severity.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
788 citations
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February 2007 in “Nature” This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.
479 citations
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January 2005 in “BioEssays” This review introduces the morphological and molecular principles of hair follicle development but reports no new experimental results, focusing on recent insights and forming a working hypothesis.
417 citations
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September 2005 in “PLoS biology” This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.
271 citations
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May 2019 in “Cells” This review discusses the therapeutic potential of MSC-derived secretomes for treating degenerative and inflammatory diseases, reporting no new clinical results but highlighting their proposed mechanisms and advantages over direct MSC transplantation.
260 citations
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December 2012 in “Cold Spring Harbor Perspectives in Biology” This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
194 citations
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May 2000 in “Journal of Investigative Dermatology” This study demonstrated that blocking the Sonic hedgehog signaling pathway in mice led to reversible inhibition of body coat hair morphogenesis, while whisker development was unaffected.
179 citations
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April 2012 in “Nature Communications” This study demonstrates the potential of using bioengineered follicles from adult tissue-derived stem cells for fully functional hair regeneration, illustrating possible applications in organ replacement therapy.
103 citations
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November 2014 in “Journal of Cell Biology” This study found that overexpression of miR-214 in keratinocytes inhibits hair follicle development and cycling by targeting β-catenin in the Wnt signaling pathway.
99 citations
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July 2017 in “Clinical Reviews in Allergy & Immunology” This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
88 citations
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July 2008 in “Development” This study shows that BMP2 and BMP7 play complex, necessary roles in feather development by regulating dermal condensation formation, with BMP7 acting early as a chemoattractant and BMP2 halting cell migration.
86 citations
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October 2013 in “Dermatologic Clinics” Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.
82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
82 citations
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May 2009 in “Development” This study found that downregulation of EGF and KGF signaling is necessary for hair follicle initiation in placodes, revealing a new role for KGF in hair follicle formation in mice.
72 citations
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July 2012 in “Journal of Investigative Dermatology” This study found that mice with a specific loss of DNA methyltransferase 1 showed uneven epidermal thickness, reduced hair regeneration, and progressive alopecia, emphasizing DNA methylation's role in stem cell homeostasis.