41 citations
,
September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.
40 citations
,
January 2016 in “Elsevier eBooks” This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
39 citations
,
August 2018 in “Scientific reports” This study demonstrated that tight junction barriers exist in human hair follicles but are less tight in hair follicle keratinocytes than in interfollicular keratinocytes, highlighting claudin-1's key role in follicle barrier function and growth.
37 citations
,
January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
26 citations
,
May 2021 in “International Journal of Molecular Sciences” In this review, researchers examined the physiological benefits of Cheonggukjang, a salt-free fermented soybean paste, highlighting its various health-promoting components that may contribute to improved heart health, diabetes management, and cancer prevention, among other benefits.
25 citations
,
July 2019 in “Journal of drug delivery science and technology” This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.
25 citations
,
January 2017 in “Steroids” This study found that the progesterone metabolite 3α-THP increased the proliferation and gene expression of human glioblastoma cells, suggesting a role in tumor progression.
21 citations
,
November 2017 in “Livestock science” This study confirms the presence of large structural variations in the genome of Nellore cattle, which may contribute to their environmental adaptation to tropical regions.
21 citations
,
September 2008 in “Magnetic Resonance Imaging” This study utilized magnetic resonance imaging to noninvasively visualize and differentiate skin structures in rat skin, finding a significant correlation between MRI data and histological areas.
16 citations
,
December 2011 in “Actas Dermo-Sifiliográficas” This review discusses the current understanding of propranolol's use in treating infantile hemangiomas, covering its indications, effectiveness, side effects, and ongoing clinical trials, without presenting new clinical results.
13 citations
,
December 2019 in “Nutrients” In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.
13 citations
,
March 2017 in “Genomics” This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.
10 citations
,
August 2024 in “Clinical Cosmetic and Investigational Dermatology” This review reports that natural compounds show promise in slowing skin photoaging by targeting cellular pathways in keratinocytes and fibroblasts. However, comprehensive clinical studies are needed to verify their efficacy and safety.
9 citations
,
May 2019 in “Experimental Cell Research” This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.
6 citations
,
May 1997 in “Journal of Dermatological Science” This study found that a gene from hamster flank organs is indirectly regulated by androgens, despite lacking direct androgen responsive elements, indicating involvement of androgen-dependent transcription factors.
5 citations
,
October 2024 in “International Journal of Biological Sciences” This study found that a specific fragment of AIMP1, secreted by hair follicle stem cells, activated dermal papilla cells, leading to enhanced hair regrowth and maintenance in mice.
4 citations
,
January 2025 in “Journal of Materials Chemistry B” In this study, researchers developed a multifunctional, injectable hydrogel that adapts to irregularly shaped wounds, enhances healing, and shows potential antibacterial activity without significant toxicity, suggesting promise for treating chronic wounds.
3 citations
,
January 2023 in “Agriculture and Natural Resources” This study found that flower extracts of Wedelia trilobata may serve as a promising active ingredient for cosmeceutical products due to their antioxidant, anti-inflammatory, and antimicrobial properties.
3 citations
,
October 2021 in “Letters in Applied NanoBioScience” This article explores the integration of nanotechnology and cosmetics, highlighting the development of cosmeceuticals targeting issues such as wrinkling, hyperpigmentation, and skin dehydration, while also reviewing cosmetic history and types of nanotechnology by particle size.
2 citations
,
January 2017 in “Journal of Biotechnology Research Center” This study found that hair dyes significantly affect DNA sequence analysis, with the organic extraction method performing better on hair shafts and the prepFiler kit yielding higher success for follicle-included samples.
1 citations
,
June 2025 in “Frontiers in Bioengineering and Biotechnology” This review examines glycopeptide hydrogels as biomimetic materials for tissue regeneration and other biomedical applications, describing their design, properties, and potential uses, and highlighting future advancements in replicating natural tissue environments for precision medicine.
1 citations
,
July 2023 in “Nature communications” This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.
January 2024 in “International Journal of Research Publication and Reviews” The herbal hair serum with rosemary, hibiscus, and neem is safe and effective for hair care.
January 2024 in “Journal of chemical health risks” In this study, gold nanoparticles-embedded ceria nanoparticles with enhanced antioxidant activities effectively reduced inflammation and colon injury in a colitis mouse model, suggesting their potential as a nano-therapeutic for inflammatory bowel disease.
July 2023 in “Indian Journal of Animal Health” This study found that fibroblast growth factor 5 may enhance Cashmere goat hair growth by altering the expression of specific genes related to keratin and keratin-associated proteins.
This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.
556 citations
,
September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.
245 citations
,
January 1998 in “Genes & Development” This study found that Hoxc13 mutations in mice cause defects in hair, nail, and tongue structures, with the most noticeable issue being brittle hair leading to alopecia.
75 citations
,
September 2017 in “Developmental biology” This review discusses circadian clock regulation in stem cells and its role in processes like neurogenesis, but reports no new results; the authors emphasize its significance in stem cell function across various tissues.
67 citations
,
February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.