research Interventions for Morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
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research Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Neutrophils Promote CXCR3-Dependent Itch in the Development of Atopic Dermatitis
Neutrophils are key in causing chronic itch in atopic dermatitis, and blocking CXCR3 could reduce this itch.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research Potential of Delonix Polymeric Nanoparticles Containing Isotretinoin for Acne Treatment
Delonix polymeric nanoparticles with isotretinoin effectively treat acne by targeting hair follicles and reducing skin irritation.
research The Potential Application of Nanocarriers in Delivering Topical Antioxidants
Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.
research Panel Discussion: The Efficacy of Retinoids in the Treatment of Psoriasis
Retinoids help treat psoriasis effectively, but they can cause side effects and need more research on safe use with other treatments.
research CRISPR/Cas9-Mediated VDR Knockout Plays an Essential Role in the Growth of Dermal Papilla Cells Through Enhanced Relative Genes
Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering
PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
research Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
research Associations of Resilience with Quality of Life in Patients with Hidradenitis Suppurativa
People with hidradenitis suppurativa who are more resilient tend to have better quality of life and less anxiety and depression.
research Malignant Epithelial Tumors: Part II. Therapy and Prevention
The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.
research Hair Loss, Body Height and Attractiveness Malus for Men
Men with hair loss are seen as less attractive and shorter, and height is a key factor in attractiveness ratings.
research Molecular Characterization of HOXC8 Gene and Methylation Status Analysis of Its Exon 1 Associated with the Length of Cashmere Fiber in Liaoning Cashmere Goat
The methylation of the HOXC8 gene's exon 1 affects cashmere fiber length in goats.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research The Neuroscience of Age Perception
Humans can accurately guess age from faces, with women being slightly better at it, and age perception is linked to evolutionary factors.
research Evaluation of Hair Density and Hair Diameter in the Adult Thai Population Using Quantitative Trichoscopic Analysis
Thai people's hair density decreases with age and varies by scalp area, but hair thickness stays the same regardless of age or scalp area.
research Implanted Hair-Follicle-Associated Pluripotent Stem Cells Aid Wound Healing and Reduce Scarring in Mice
Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
research The Expanded Flying-Wings Scalp Flap for Aesthetic Hemiscalp Alopecia Reconstruction in Children
The "flying-wings" scalp flap technique is a simple, safe, and effective way to reconstruct large areas of scalp loss in children.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research Minoxidil and the Treatment of Severe Hypertension
Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
research Characteristic Findings by Phototrichogram in Southern Chinese Women with Female Pattern Hair Loss
Southern Chinese women with female pattern hair loss have less, thinner hair and smaller hair follicles.
research New Changes in Pregnancy and Lactation Labeling: Review of Dermatologic Drugs
The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.
research The Trichoscopy Derived Sinclair Scale: Enhancing Visual Assessment Through Quantitative Trichoscopy
The Trichoscopy Derived Sinclair Scale offers a more accurate and reliable way to measure hair loss severity than the traditional visual method.
research Spatiotemporal Dynamics of Sensory Neuron and Merkel-Cell Remodeling During Epidermal Homeostasis
Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.
research The Fraser Complex Proteins Can Form Anchoring Cords Without AMACO at the Dermal-Epidermal Junction of Mouse Skin
Certain skin proteins can form anchoring structures without the protein AMACO.
research Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells
β-catenin is essential for stem cell activation and proliferation in hair follicles.
research Health Utility Measures Among Patients With Androgenetic Alopecia After Hair Transplant
research Reporting on Adverse Clinical Events
The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.