January 2026 in “Dermatologic Therapy” This study found that a shampoo containing 1% selenium sulfide and 1% salicylic acid significantly improved the clinical signs and symptoms of seborrheic dermatitis and dandruff over an 8-week period.
January 2008 in “Journal of The American Academy of Dermatology” Hair loss affects 20% of people, more in men and those over 35, and is often associated with a sensitive scalp.
September 2024 in “Journal of the American Academy of Dermatology” This introduction highlights that a common challenge with managing dandruff, a mild form of seborrheic dermatitis, is compliance with treatment, and notes that selenium disulfide shampoo is beneficial for this condition.
July 2026 in “Journal of the American Academy of Dermatology” October 2023 in “IP Indian Journal of Clinical and Experimental Dermatology” This study demonstrated that a 12-week treatment with luliconazole-containing shampoo significantly reduced scalp scaling, erythema, and itching in adults with seborrheic dermatitis, achieving high tolerability and progressive symptom improvement without reported intolerance or recurrences.
8 citations
,
November 2022 in “Cureus” In this study, patients with mild to moderate scalp seborrheic dermatitis experienced greater improvements in severity scores and quality of life with Lulican™ shampoo compared to Ketoconazole over four weeks, with similar safety profiles but better tolerability and cosmetic acceptability for LulicanTM.
5 citations
,
February 2022 in “East African Journal of Science Technology and Innovation” This study evaluated a herbal shampoo containing flavonoid glycosides from Dicerocaryum senecioides and found that it successfully treated T. tonsurans infections in children's scalp when used daily, demonstrating significant effectiveness compared to a placebo.
March 2025 in “Skin Appendage Disorders” In this study, selenium disulfide shampoo was found to reduce dandruff severity and rebalance the scalp microbiome in individuals with all hair types experiencing moderate to severe dandruff, with subjects reporting high satisfaction and good tolerance over a 6-week period.
3 citations
,
March 2005 in “Journal of the American Academy of Dermatology” This case report describes a patient with Birt-Hogg-Dube syndrome exhibiting multiple fibrofolliculomas, acrochordons, and renal oncocytoma.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that a shampoo containing a 6-active ingredient complex increased β-Catenin production in human hair follicle dermal papilla cells to levels comparable to Finasteride, suggesting potential for promoting hair growth. It also showed good cleaning efficacy, volume, and shine in a sensorial study.
7 citations
,
March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
January 2024 in “Journal of Dermatology & Cosmetology” This study found that the ThriveCo Anti-Dandruff Pre-Shampoo Treatment, containing ZenscalpinTM, significantly reduced dandruff by 54.79% after 8 days and improved scalp health, with most participants reporting reduced flaking, dryness, and itchiness, and no noted adverse events.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that a formulated polyherbal shampoo demonstrated effective antifungal properties against dandruff-causing fungi, with smooth, intact hair cuticles after treatment, suggesting it may serve as a safe, natural alternative for managing dandruff.
November 2010 in “Deleted Journal” This study reported that a newly formulated clear liquid shampoo with lavender oil may be effective and acceptable for dandruff control and overall hair and scalp hygiene, based on tests with twenty volunteers.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated a polyherbal shampoo from plant extracts, finding it showed effective antifungal properties against dandruff-causing agents like Malassezia species while providing protective and conditioning effects on hair cuticles, indicating its potential as a natural alternative for dandruff management.
16 citations
,
January 2000 in “Journal of dermatological treatment” This study found that calcipotriol scalp solution was more effective than a coal tar-based shampoo for treating mild to moderate scalp psoriasis and showed continued efficacy with long-term use.
January 2002 in “China Surfactant Detergent & Cosmetics” This study compared shampoos and found that shampoo D, containing polyquaternium-10, guar gum, and dimethicone, was most effective in restoring chemically permed hair.
35 citations
,
April 1956 in “Journal of the American Medical Association” This study found that using selenium sulfide shampoo for seborrheic dermatitis was associated with hair loss, which ceased after discontinuing the shampoo.
January 2019 in “프로그램북(구 초록집)” This study found that synthetic ceramide shampoo improved dandruff and erythema while reducing water loss when compared to control in a group of 20 subjects over four weeks.
2 citations
,
January 2013 in “Journal of cosmetics, dermatological sciences and applications” This study found that both an anti-dandruff shampoo containing piroctone olamine and climbazole and its combination with a tonic reduced dandruff and inflammation, with the combination showing superior results.
May 2025 in “Journal of Dermatological Treatment” This study found that a medicated shampoo containing selenium sulfide and salicylic acid effectively reduced symptoms of seborrheic dermatitis in Chinese patients, but females experienced significantly lower rates of good effectiveness and tolerance compared to males.
April 2025 in “Research Journal of Topical and Cosmetic Sciences” This study found that an anti-dandruff shampoo containing Bromelain effectively preserves hair fiber integrity, enhances uniformity and lustre, and offers therapeutic benefits for scalp infections and inflammation, making it a safer alternative for dandruff treatment.
25 citations
,
January 2019 in “Journal of Pharmacy And Bioallied Sciences” This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.
March 2024 in “International Research Journal of Modernization in Engineering Technology and Science” In this study, researchers developed a herbal shampoo using natural plant extracts, which maintained physicochemical properties and improved hair texture without the side effects commonly associated with synthetic ingredients.
14 citations
,
January 2020 in “Skin appendage disorders” This study found that a shampoo containing 0.075% broad-spectrum cannabidiol significantly reduced scalp inflammation and symptoms in subjects with mild to moderate scalp psoriasis or seborrheic dermatitis within two weeks.
20 citations
,
January 1990 in “Journal of dermatological treatment” This study found that both ketoconazole 2% shampoo and selenium sulphide are effective for dandruff treatment, but ketoconazole also reduces hair growth.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a herbal anti-dandruff shampoo using natural ingredients, finding that it effectively reduced dandruff, improved scalp and hair health, and presented an economical and safe alternative to synthetic shampoos without significant skin irritation.
February 2023 in “Deleted Journal” This study aimed to create and assess an herbal shampoo that prioritizes safety, efficacy, and quality, as an alternative to conventional shampoos that can cause side effects such as hair loss and scalp irritation.
July 2026 in “International journal of research in pharmacy and life sciences.” This study formulated and evaluated a polyherbal anti-dandruff shampoo, demonstrating it had good cleansing properties, antimicrobial activity against dandruff-causing microbes, and remained physically stable, potentially offering a safe and effective herbal alternative for dandruff management.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed and tested a herbal shampoo incorporating natural extracts like curry leaves, neem, and fenugreek, finding that these formulations reduced dandruff and improved hair health while being non-irritating and stable; the curry leaf shampoo excelled in cleansing performance.