This study suggests that using cell-free dexamethasone-primed stem cell media may offer a promising alternative treatment for systemic lupus erythematosus, showing immunomodulatory benefits and therapeutic efficacy in reducing various complications.
45 citations
,
September 1998 in “Journal of Investigative Dermatology” This study found that sebaceous glands predominantly exhibit oxidative activity of the type 2 17β-hydroxysteroid dehydrogenase isozyme, which is not inhibited by 13-cis retinoic acid.
39 citations
,
September 2018 in “American Journal of Medical Genetics Part A” This case report describes a 32-month-old girl with a newly identified pediatric disorder linked to a de novo mutation in the ODC1 gene, mirroring symptoms seen in a transgenic mouse model.
16 citations
,
October 2013 in “Anais Brasileiros de Dermatologia” In this case report, an elderly woman with erosive pustular dermatosis of the scalp showed complete closure of eroded areas after treatment with prednisone and topical tacrolimus, resulting in stable scarring alopecia.
June 2025 in “Scholars Journal of Medical Case Reports” This case report highlights that trichoscopy facilitated early diagnosis of discoid lupus erythematosus of the scalp in a 9-year-old boy, with oral prednisone minipulse therapy leading to complete remission and hair regrowth.
September 2024 in “Journal of the American Academy of Dermatology” Teledermatology can effectively treat certain skin conditions with topical treatments, reducing the need for in-person visits.
April 2018 in “Blackwell's Five‐Minute Veterinary Consult Clinical Companion” This chapter reviews common dermatoses in small animals and offers bulleted lists as a preliminary tool for formulating differential diagnoses, but reports no new clinical findings.
May 2018 in “Dermatologic Surgery” This overview describes the Dermatologic Surgery journal's extensive coverage of cosmetic and reconstructive skin surgery, but it reports no new research findings.
5 citations
,
August 2021 in “Frontiers in Cell and Developmental Biology” This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.
1 citations
,
September 2024 in “Journal of the American Academy of Dermatology” Farudodstat may effectively treat alopecia areata without harmful side effects.
This study explores the expression and function of 11β-HSD1 in human hair follicles and its potential regulation of glucocorticoid effects on dermal papilla cells, but reports no definitive findings on 11β-HSD1's role.
49 citations
,
December 2017 in “Journal of pharmaceutical and biomedical analysis” This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.
5 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.
July 2026 in “Journal of Investigative Dermatology”
May 2026 in “Drug Delivery and Translational Research” Nanocarriers with spironolactone and 2-deoxy-D-ribose may improve hair loss treatment by targeting hair follicles directly.
7 citations
,
January 2007 in “PubMed” This review discusses the use of videodermoscopy in evaluating scalp and hair disorders, highlighting its potential to improve diagnostic accuracy without the need for invasive biopsies, but notes that further prospective studies are needed.
4 citations
,
December 2022 in “Advanced science” This study found that fatty acid desaturation regulated by SCD1 is crucial for hair growth by maintaining hair follicle stem cell niches, with its absence causing abnormal hair growth in mice.
January 2026 in “Journal of Materials Chemistry B” In this study, researchers developed a delivery system using a deep eutectic solvent to improve hydroxytyrosol absorption for hair regrowth, achieving over threefold greater skin penetration compared to aqueous solutions and demonstrating its effectiveness and biocompatibility in hair regrowth and ROS-scavenging tests.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no elevation of serum DHEA-S levels in men with androgenetic alopecia and observed no correlation between DHEA-S levels and the clinical stage of the condition.
May 2014 in “Journal of The American Academy of Dermatology” The project aimed to understand how genetic test results affect patients' actions and feelings in dermatology.
16 citations
,
June 1992 in “PubMed” In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.
December 2021 in “Skin appendage disorders” This study developed and validated an objective dermoscopic severity score for evaluating female pattern hair loss, which may serve as a supplementary outcome measure in therapeutic trials.
12 citations
,
January 2016 in “Journal of clinical biochemistry and nutrition” In this study, combining deferasirox with sorafenib significantly reduced liver fibrosis and preneoplastic lesions in rats while also lessening adverse effects compared to sorafenib alone.
2 citations
,
January 2006 in “Technical report” This chapter reviews the development of skin-specific outcome instruments for autoimmune diseases like cutaneous lupus erythematosus and dermatomyositis, highlighting a need for a broader community-involved process across other diseases but reports no new results.
12 citations
,
September 2015 in “Drug Design Development and Therapy” This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.
20 citations
,
September 2019 in “Epidemiology and Psychiatric Sciences” This review discusses post-SSRI sexual dysfunction syndrome and highlights its significant clinical and regulatory implications, but reports no new findings.
April 2017 in “Journal of Investigative Dermatology” In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” This study found that women with PCOS have higher activity of the enzyme 5alpha-reductase, which may contribute to their elevated androgen levels.
22 citations
,
January 1999 in “Dermatology” This case report describes a rare instance of double-lined frontoparietal scleroderma en coup de sabre and suggests a genetic basis involving postzygotic mosaicism.