Post-SSRI Sexual Dysfunction and Other Enduring Sexual Dysfunctions

The document discussed enduring sexual difficulties following treatment with selective serotonin reuptake inhibitor (SSRI) antidepressants, which had been reported since 1991. However, it was not until 2006 that a formal post-SSRI sexual dysfunction syndrome was recognized. The syndrome had significant clinical, research, and regulatory implications. Researchers using epidemiological methods were considered well-positioned to explore the extent of the problem and potentially identify treatments.