Persistent Adverse Effects of Antidepressants

    Joanna Moncrieff
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    TLDR Antidepressants can cause long-term side effects like severe withdrawal symptoms and sexual dysfunction, which can last for months or years after stopping the medication.
    The document from 2019 discussed the persistent adverse effects of antidepressants, focusing on withdrawal effects and post-SSRI sexual dysfunction. It highlighted that antidepressants, which alter the normal functioning of the brain, can disrupt normal biological processes with potentially devastating consequences for some users. The exact nature of these changes and their long-term effects were not fully understood. The document also noted that withdrawal effects, which can be severe and protracted, are common with antidepressants. Additionally, it discussed post-SSRI sexual dysfunction, a condition that can persist for months or years after cessation of the drugs. A survey identified that 34% of respondents showed evidence of possibly having the condition, and 4.3% showed a high probability of having it. The document concluded that there was a large-scale failure to appreciate the risks involved in taking drugs that alter brain function on a long-term basis.
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