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Did you mean Selective Serotonin Reuptake Inhibitors?

Glossary Selective Serotonin Reuptake Inhibitors

medications that increase serotonin levels to treat depression

Selective Serotonin Reuptake Inhibitors (SSRIs) are a class of medications commonly used to treat depression and anxiety disorders. They work by increasing the levels of serotonin, a neurotransmitter, in the brain by inhibiting its reabsorption (reuptake) into neurons, thereby enhancing mood and emotional stability.

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research Cutaneous effects of the most commonly used antidepressant medication, the selective serotonin reuptake inhibitors

55 citations , December 2006 in “Journal of The American Academy of Dermatology”

This review discusses the potential for SSRIs to cause serious skin reactions and suggests considering alternative antidepressants if such reactions occur.

research Alopecia associated with treatment with selective serotonin reuptake inhibitors (SSRIs)

25 citations , January 2006 in “Pharmacoepidemiology and drug safety”

This study concluded that alopecia is a rare side effect of SSRIs, with sertraline showing a higher association compared to citalopram, particularly among women.

Trazodone and Chlorpromazine: A Proposed Treatment for Post-Finasteride Syndrome and Post-SSRI Syndrome

research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)

July 2023 in “World Journal of Biology Pharmacy and Health Sciences”

This research suggests that the drugs trazodone and chlorpromazine, which have effects on specific receptors, may help restore libido synaptic circuits and potentially treat sexual dysfunction associated with post-SSRI and post-finasteride syndromes.

research The Off-Label Use of Selective Serotonin Reuptake Inhibitors for Sexual Behavior Management: Risks and Considerations

September 2025 in “Healthcare”

This review discusses the off-label use of SSRIs to manage inappropriate sexual behavior in elderly dementia patients and highlights the unclear risk of post-SSRI sexual dysfunction, noting a need for high-quality clinical trials.

Trazodone and Chlorpromazine: A Proposal Treatment for Post-Finasteride Syndrome and Post-Selective Serotonin Reuptake Inhibitors Syndrome

research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)

July 2023 in “Zenodo (CERN European Organization for Nuclear Research)”

In this study, the authors propose that drugs like trazodone and antipsychotics such as chlorpromazine, which can induce priapism, may help restore libido synaptic circuits, offering potential treatment for post-finasteride syndrome and post-SSRI sexual dysfunction.

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community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community Hair loss over a year following depression and taking antidepressants

in Side effects? 200 upvotes 8 months ago

A 33-year-old experienced significant hair loss after a depressive episode and taking paroxetine, possibly due to telogen effluvium or androgenic alopecia. Suggestions included reducing alcohol, considering finasteride and minoxidil, and consulting a doctor about antidepressant side effects.

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