Study Design for the Stanford Dermatology Personal Genomics Project

The Stanford Dermatology Personal Genomics Project was designed to assess the impact of direct-to-consumer (DTC) genomic analysis on patient behavior, risk perception, emotional response, and medical use within dermatology. The study planned to recruit 10,000 participants from the Stanford Dermatology Clinic who had chosen to undergo DTC genotyping. Participants were to complete a baseline survey before testing to establish their skin health practices and knowledge about genetic testing. After receiving their genetic risk results for skin cancer, atopic dermatitis, and androgenetic alopecia, participants would be given recommendations on behavioral modifications. Follow-up surveys at 3 and 6 months post-testing were intended to evaluate changes in behavior, psychological well-being, and medical use. The study aimed to provide insights into the effects of dermatology-relevant genetic risk information on patients and to encourage other investigators to adapt this study design for further research.