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    Glossary Drug Targets

    specific molecules drugs interact with to produce therapeutic effects

    Drug targets, also known as pharmacological targets or therapeutic targets, are specific molecules in the body, often proteins, that drugs interact with to produce a therapeutic effect. These targets can include enzymes, receptors, ion channels, or other proteins involved in disease processes. By binding to these targets, drugs can modify their activity, leading to changes in cellular function and ultimately improving health outcomes.

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    1. Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery AAPS PharmSciTech · 2009 · 32 citations
    2. Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles Pharmaceutics (Basel) · 2023 · 4 citations
    3. An update on nanocarriers for follicular-targeted drug delivery for androgenetic alopecia topical treatment Expert Opinion on Drug Delivery · 2025
    4. Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets Frontiers in Physiology · 2025 · 1 citations
    5. Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders Asian Journal of Pharmaceutical Sciences · 2022 · 14 citations
    6. Dual-drug nanostructured lipid carriers of spironolactone and 2-deoxy-D-ribose for targeted follicular delivery in androgenetic alopecia Drug Delivery and Translational Research · 2026
    7. Multi-targeted synergy of Bacillus sp. TC5 fermentation products for transdermal drug delivery and hair regeneration Journal of Advanced Research · 2026
    8. New drug targets and research methods for androgenetic alopecia Folia Pharmacologica Japonica · 2009 · 2 citations
    9. Uncovering novel biomarkers and drug targets for androgenetic alopecia via metabolite regulation and multi-tissue validation Free Radical Biology and Medicine · 2025
    10. Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic (TMDD-PD) Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-linear Pharmacokinetics The AAPS Journal · 2025
    11. Drug repositioning approach to target ‎viral and host cells in terms of COVID-19 treatment: A review of ‎in vivo experiments and clinical studies Journal of experimental and clinical medicine · 2022
    12. Hair Follicle Targeting and Dermal Drug Delivery with Curcumin Drug Nanocrystals—Essential Influence of Excipients Nanomaterials · 2020 · 32 citations
    13. Diagnosis and treatment of cutaneous adverse effects of targeted therapy, antibody–drug conjugates, and immunotherapy in cancer patients: a national consensus statement by the Spanish Society of Medical Oncology and the Spanish Academy of Dermatology and Venereology Clinical & Translational Oncology · 2026
    14. Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance Genes & Diseases · 2023 · 56 citations
    15. Advances in structure-based drug design targeting membrane protein markers in prostate cancer Drug Discovery Today · 2024 · 5 citations
    16. Nanostructured Drug Delivery Systems for Targeting 5-α-Reductase Inhibitors to the Hair Follicle Pharmaceutics · 2022 · 3 citations
    17. Abstract 4350: Pharmacodynamic biomarkers: Evaluation of oncology drug target engagement in human plucked scalp and beard hair Cancer Research · 2023
    18. Niosomal Nanoformulations for Targeted Follicular Drug Delivery in Alopecia: An Integrative Review of Pathophysiology, Therapies, and Nanotechnology-Based Approaches Journal of advanced Biomedical and Pharmaceutical Sciences · 2026
    19. Roles of existing drug and drug targets for COVID-19 management Metabolism Open · 2021 · 26 citations
    20. Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions Journal of Nutrition and Metabolism · 2023
    21. Niosomes: A Novel Targeted Drug Delivery System 2021 · 3 citations
    22. Novel Drug Delivery Systems and Emerging Molecular Targets in Androgenetic Alopecia: A Comprehensive Review of Next-Generation Therapeutics SSRN Electronic Journal · 2026
    23. DNN-DTIs: improved drug-target interactions prediction using XGBoost feature selection and deep neural network bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 3 citations
    24. Lipid-based nanocarriers coupled with CO 2 laser-mediated drug delivery enhance skin penetration and hair follicle targeting Journal of drug targeting · 2026
    25. Developing formulations for drug follicular targeting: Nanoemulsions loaded with minoxidil and clove oil Journal of drug delivery science and technology · 2020 · 19 citations
    26. Design of a targeted drug delivery system to reshape the perifollicular microenvironment in androgenetic alopecia 2022
    27. Iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles accelerates drug release, decreasing their targeting effect to hair follicles Química Nova · 2016 · 2 citations
    28. Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid Current medicinal chemistry · 2013 · 21 citations
    29. Targeting PrfA from Listeria monocytogenes: a computational drug repurposing approach bioRxiv (Cold Spring Harbor Laboratory) · 2023
    30. Cytochrome P450: A Target for Drug Development for Skin Diseases 2004 · 115 citations