September 2018 in “Value in Health” Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.
Off-label drug use can be risky but sometimes beneficial when standard treatments fail.
105 citations,
December 2009 in “Archives of dermatology” A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.
74 citations,
March 2006 in “Journal of Chromatography B” Hair analysis is promising for detecting drug misuse in livestock.
71 citations,
November 2012 in “Expert Opinion on Drug Safety” 5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.
42 citations,
January 2019 in “Frontiers in Immunology” A blood pressure drug, diltiazem, may also help treat influenza.
40 citations,
July 2018 in “European Journal of Pharmaceutical Sciences” Melatonin vitamin C-based nanovesicles improved hair growth and reduced hair loss in androgenic alopecia patients.
29 citations,
January 2010 in “Methods in Enzymology” The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
16 citations,
March 2013 in “JAMA Dermatology” A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.
8 citations,
August 2018 in “International Journal of Dermatology” The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
5 citations,
December 2015 in “Dermatologic Therapy” Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.
2 citations,
January 2016 Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.
1 citations,
December 2023 in “Nanomaterials” Combining specific nanoparticles with immune therapy significantly improves cancer treatment.
November 2023 in “Children” Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.
August 2023 in “Dataset Reports” Social media influencers often promote self-medication, which can be dangerous without professional guidance.
January 2022 in “Elsevier eBooks” Nanospanlastics are effective in targeted drug delivery for chronic diseases, improving skin conditions, treating hair loss, and increasing drug absorption.
September 2023 in “Journal of Nutrition and Metabolism” One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
August 2022 in “Scholars academic journal of pharmacy” Invasomes loaded with clotrimazole gel could improve drug delivery through the skin for fungal treatment.
April 2023 in “European urology open science” Urologists should screen for mental health issues before and during finasteride treatment.
February 2023 in “European Journal of Medical Research” Certain existing drugs, like glycopyrronium and botulinum toxin type A, may help treat excessive sweating.
421 citations,
January 2015 in “Chemical Society Reviews” Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.
125 citations,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
45 citations,
January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
34 citations,
February 2015 in “Frontiers in Cellular Neuroscience” Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
15 citations,
February 2019 in “Journal of clinical medicine” Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
9 citations,
June 2022 in “Composites. Part B, Engineering” The new dressing with silver nanowires and collagen on bacterial cellulose heals wounds effectively with less toxicity and good antibacterial properties.
8 citations,
March 2019 in “Drugs - Real World Outcomes” Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
7 citations,
January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
5 citations,
August 2020 in “Stem Cell Research & Therapy” Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
4 citations,
January 2023 in “Journal of Human Hypertension” Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.