July 2005 in “Indian Journal of Dermatology” This study found that finasteride significantly promoted hair growth compared to placebo in male patients with androgenic alopecia, but also noted a high incidence of sexual side effects.
9 citations
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June 2020 in “Trials” This study aims to conduct the first double-blind randomized trial comparing spironolactone and doxycycline for female acne treatment, with the goal of establishing spironolactone as a potentially superior alternative, especially given concerns about antibiotic resistance.
August 2023 in “Stem Cell Research & Therapy” In this study on male androgenetic alopecia, the researchers reported significant increases in hair count, density, and thickness with minimal side effects over 6 weeks using adipose-derived stem cell conditioned media and minoxidil, but found no significant differences between concentrated and non-concentrated treatments.
37 citations
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January 1980 in “PubMed” This study found that topical hair lotions with 17 alpha-estradiol may reduce telogen hair loss in patients with androgenetic alopecia, though they did not lead to new hair regrowth.
2 citations
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February 2023 in “F&S Reports” This study found that elagolix treatment did not normalize the ovulatory cycle in patients with polycystic ovarian syndrome.
March 2026 in “Journal of Dermatological Treatment” In this randomized, double-blind, placebo-controlled trial, topical 3% minoxidil was found to significantly improve facial hair density and diameter, quality of life, and patient satisfaction in transgender men on stable gender-affirming hormone therapy, with minimal adverse events compared to placebo.
April 2025 in “Cosmetics” In this randomized, double-blind study, a shampoo containing Plantago asiatica L. significantly improved hair thickness and density while reducing hair loss over 12 weeks in adults compared to a placebo.
March 2025 in “Chinese Medical Journal” This randomized, double-blind, placebo-controlled phase III trial found that a 24-week treatment with topical finasteride significantly increased hair growth and was well-tolerated in Chinese men with androgenetic alopecia compared to placebo.
March 2025 in “Plastic & Reconstructive Surgery Global Open” This study reported that participants applying topical human platelet exosome extract serum experienced significant improvements in hair volume, density, scalp coverage, and overall hair health compared to a placebo, and no adverse effects were observed.
January 2025 in “Journal of Cosmetic Dermatology” This study suggests that addressing hormonal, stress, and metabolic factors with vitamins, minerals, and botanicals, which has improved hair growth in women, might also benefit men experiencing hair thinning.
December 2022 in “Archives of Dermatological Research” This study found that topical cetirizine increased hair shaft thickness and improved clinical outcomes from the patients' perspective in female androgenetic alopecia compared to minoxidil alone, with similar side effect profiles.
5 citations
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November 2020 in “medRxiv (Cold Spring Harbor Laboratory)” In this study, the authors reported that dutasteride significantly reduced total remission time for COVID-19 symptoms in men compared to placebo, especially for fatigue and loss of taste or smell.
4 citations
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February 2025 in “Nutrients” This randomized controlled trial found that consuming *Gynostemma pentaphyllum* extract significantly improved hair elasticity, density, and diameter over 24 weeks without severe adverse events, suggesting it as a safe functional food ingredient for hair health improvement.
4 citations
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December 2019 in “Trials” This study aims to evaluate the effectiveness of YH0618 granules in preventing chemotherapy-induced hair loss in breast cancer patients through a randomized, double-blind, multi-center clinical trial, focusing on potential mechanisms related to kidney deficiency as understood in Chinese Medicine. Results are not yet reported.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
This phase II study found that a 0.05% topical dutasteride solution was more effective than oral finasteride (1 mg/day) in increasing hair count and width in males with androgenetic alopecia over 24 weeks, without causing irritation.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
In this study, researchers found that autologous PRP injections, when used as an adjuvant treatment with topical minoxidil, did not provide a significant increase in hair density compared to placebo in men with androgenetic alopecia in northeastern India.
September 2023 in “Journal of the American Academy of Dermatology” Guselkumab effectively reduces fatigue in Psoriatic Arthritis patients over two years.
January 2023 in “Dermatologic Therapy” In this randomized controlled trial, the nutritional supplement PPT5 α was associated with increased terminal hair percentages and improved self-assessed hair parameters in women with early-stage androgenetic alopecia.
January 2023 in “Indian Journal of Dermatology, Venereology and Leprology” In this study, activated platelet-rich plasma improved hair density and thickness in patients with androgenetic alopecia, with higher platelet counts enhancing these effects over time.
July 2021 in “Journal of reports in pharmaceutical sciences” This study evaluated a new aqueous-based nanosuspension of minoxidil for treating androgenetic alopecia and reported it was as effective as the commercial product but had better safety and tolerability, potentially improving patient compliance.
May 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
July 2024 in “Skin Appendage Disorders” This study found that after 6 months of taking an oral supplement, patients with chronic telogen effluvium or androgenetic alopecia experienced a statistically significant increase in hair density and overall improved hair appearance compared to those taking a placebo, with the supplement being well tolerated.
6 citations
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October 1983 in “PubMed” This study found no significant protective effect of coenzyme Q10 on hair loss from anthracycline antibiotics, although liver enzyme elevations were less frequent with CoQ10.
July 2025 in “Annals of Medicine” This study describes a planned multicenter randomized controlled trial to assess the safety, tolerability, and pharmacokinetics of subdermal gestrinone pellets in patients with deep infiltrative endometriosis-related pelvic pain, but it does not report any findings yet.
21 citations
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April 2018 in “The Journal of urology/The journal of urology” This study found that SER120 nasal spray significantly improved nocturia symptoms and quality of life compared to placebo in patients 50 years and older, with both tested doses showing efficacy and an acceptable safety profile over a 12-week period.
In this clinical trial, rosemary-lavender and rosemary-castor oils were found to significantly improve hair growth rate, thickness, density, length, and reduce hair fall compared to coconut oil over 90 days, indicating they may be effective natural alternatives for hair regrowth.
3 citations
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October 2021 in “Clinical, Cosmetic and Investigational Dermatology” This study found that oral setipiprant was safe but did not improve scalp hair growth compared to placebo in men with androgenetic alopecia.
2 citations
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August 2024 in “Journal of Cosmetic Dermatology” This study suggests that combining silymarin with hair transplantation might be a promising treatment for vitiligo, but more research is needed to confirm its effectiveness.