Protective Effects of Coenzyme Q10 on Adverse Reactions of Anthracycline Antibiotics: Double-Blind Method with Special Reference to Hair Loss

    October 1983 in “ PubMed
    T Akihama, Yoshihiko Nakamoto, T. Shindo, Yuri Nakayama, Atsuhiko Miura
    Studysummary This study found no significant protective effect of coenzyme Q10 on hair loss from anthracycline antibiotics, although liver enzyme elevations were less frequent with CoQ10.
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    The study investigated the protective effects of coenzyme Q10 on hair loss caused by anthracycline antibiotics using a double-blind method. It included 19 participants with acute leukemia, blastic crisis of CML, and malignant lymphoma. Participants received either 120 mg/day of coenzyme Q10 or a placebo. The study found no significant difference in hair loss between the coenzyme Q10 and placebo groups. However, elevations of liver enzymes GOT and GPT were less frequent in the group receiving coenzyme Q10, suggesting a potential protective effect on liver function.
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