44 citations
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May 2008 in “Plant journal” This study found that D'orenone blocks root hair growth by increasing PIN2 protein abundance, leading to reduced auxin concentration, but external auxin can reverse these effects.
1 citations
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January 2015 This study found that a compound isolated from Aloe barbadensis Miller showed strong effects on hair follicle regeneration and hair growth in warfarin-induced alopecia in rats, suggesting potential as a minoxidil alternative.
2 citations
,
February 2022 in “Genomics” This study used cashmere goats to map the differentiation of dermal papilla stem cells and identified key intermediate cell states involved in hair follicle regeneration.
1 citations
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February 2021 in “Journal of Natural Remedies” This study found that a combination of Ficus religiosa and Morus alba extracts promoted hair growth and Hair Follicle regeneration in a mouse model of hair loss by inducing the anagen phase and upregulating stem cell-associated genes.
45 citations
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December 2014 in “Journal of the European Academy of Dermatology and Venereology” This study found that plasmacytoid dendritic cells are central to the pathogenesis of alopecia areata, suggesting they may help differentiate it from trichotillomania and androgenetic alopecia.
2 citations
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January 2018 This article discusses diffuse alopecia areata, highlighting its autoimmune characteristics, more intense inflammation, and challenges in diagnosis, but presents no new clinical findings.
This thesis explores the role of the actin cytoskeleton in plant cell growth, highlighting its involvement in signal transduction and the regulation of tip growth in cells like root hairs.
26 citations
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September 1999 in “Canadian Journal of Botany” This study found that a recessive mutation in the RHD4 gene of Arabidopsis thaliana leads to slower and more variable tip growth in seedling root hairs, resulting in shorter and wider hairs than in wild-type plants.
July 2023 in “New phytologist” This research identified a genetic mutation in Brachypodium distachyon that initially allows root hair initiation but fails to elongate them, while also affecting root growth and nitrate sensitivity; the mutation is linked to a previously uncharacterized cyclin-dependent kinase-like gene.
139 citations
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October 1999 in “Environmental Health Perspectives” This article reviews the scientific exploration of Ayurvedic medicinal plants and discusses their modern applications, such as a drug developed from Commiphora wightti for lipid disorders, without reporting new clinical findings.
August 2025 in “JOURNAL OF EXPERIMENTAL ZOOLOGY INDIA” This study reported that a spray containing Origanum marjoram essential oil significantly improved hair regrowth, dermal thickness, weight, and lymphocyte levels in rabbits with cyclophosphamide-induced alopecia, suggesting its potential as a natural alternative for hair loss treatment.
15 citations
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January 2015 in “Pharmaceutical Biology” In a study on nude mice, topical application of Chrysanthemum zawadskii extracts stimulated hair growth and increased hair follicle numbers, suggesting potential for alopecia therapy.
April 2025 in “International Journal of Health Sciences” This study reports that Polyscias scutellaria exhibits diverse pharmacological activities, including antibacterial, antifungal, anti-inflammatory, antioxidant, and antidiabetic properties, suggesting potential therapeutic uses in various health applications.
39 citations
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July 2016 in “Biomedicine & Pharmacotherapy” In this animal study, researchers found that cedrol, a constituent from Platycladus orientalis, significantly promoted hair growth in a dose-dependent manner in female C57BL/6 mice, surpassing results from blank control and 2% minoxidil groups over 21 days.
March 2026 in “Mammalogy Notes” In this report, the sighting of a maned wolf in a rural area of Brazil with severe hair loss, likely due to alopecia, was documented, and it was suspected that the condition resulted from disease transmission from domestic dogs.
April 2026 in “ACS Applied Materials & Interfaces” In this study, researchers developed a fast-dissolving microneedle patch delivering minoxidil nanoparticles and plant-derived vesicles, which improved hair regrowth and follicle health in a mouse model of androgenetic alopecia by reducing oxidative stress and inflammation without causing skin irritation or systemic toxicity.
477 citations
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March 2004 in “Proceedings of the National Academy of Sciences” This study reports that the DMI3 gene, essential for nodule formation in legume-rhizobial symbiosis, encodes a calcium/calmodulin-dependent protein kinase, highlighting its role in multiple plant symbioses.
June 2022 in “Journal of Cosmetic Dermatology” This study found that the ethanolic extract of Acanthus ebracteatus demonstrated potential as an anti-hair loss treatment by promoting dermal papilla cell proliferation, inhibiting 5α-reductase activity, and reducing inflammation in vitro.
51 citations
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July 2013 in “Bioorganic & Medicinal Chemistry Letters” This study found that compound 2 from Polygonum multiflorum significantly increased dermal papilla cell proliferation and hair-fiber length, suggesting potential as a therapeutic agent for alopecia.
20 citations
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February 1994 in “In vitro cellular & developmental biology. Animal” Wool follicles can grow in a lab with the right nutrients and conditions.
1 citations
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October 2001 in “Journal of Wood Science” This study found that extracts from the fungus YL161, Agaricus blazei, and the bark of Camptotheca cuminata promoted dermal papilla cell growth more effectively than pentadecanoic acid, suggesting potential for stimulating hair growth.
June 2025 in “Pharmacognosy Research” This study reviews the rich chemical composition and traditional medicinal uses of Dillenia indica, highlighting its potential therapeutic applications in various health conditions like diabetes, inflammation, and microbial infections, while noting its nutritional value in regional cuisine.
In this study, the ethanol extract of Tridax procumbens leaves exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria, with specific active compounds identified through GC-MS analysis that may contribute to its therapeutic potential.
143 citations
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October 2008 in “Journal of The American Academy of Dermatology” This study found that comma hairs are a distinctive feature of tinea capitis caused by Microsporum canis, distinguishing it from alopecia areata, which is characterized by exclamation mark hairs.
October 2012 in “Annals of Allergy Asthma & Immunology” This review discusses the distribution, habitat, and medicinal uses of the witch hazel species in the Hamamelidaceae family, reporting no new experimental results.
28 citations
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October 2004 in “Differentiation” This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.
17 citations
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December 2015 in “BMC Complementary and Alternative Medicine” This study found that Avicennia marina extract significantly inhibited 5α-reductase type 1 activity in human hair dermal papilla cells, suggesting its potential use for treating androgenic alopecia.
2 citations
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January 2011 This study found that topical 5% aqueous extract of Trichosanthes dioica R. leaves significantly promoted hair growth in rats compared to both a control and minoxidil treatment.
3 citations
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July 2021 in “International journal of pharmaceutical chemistry and analysis” This review examines the role of medicinal plants in treating hair problems like baldness and dandruff, but it reports no new clinical results and emphasizes nutritional benefits from various herbal ingredients.
July 2014 in “Planta Medica” This article reviews the use of Eclipta Alba, a traditional Ayurvedic herb, in liver health, hair growth, and diabetes management, but it reports no new research findings.