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Hair and nail cells share similar proteins, indicating a common differentiation pathway.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Fatty acid transport protein 4 is essential for skin and hair development.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Four-amino acid part makes enzyme sensitive to finasteride.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.

Prolactin affects when mice shed and grow hair.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

FOXN1 gene variants cause low T cells and immune issues from birth.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

CYLD mutations cause a variety of skin tumors with symptoms starting around age 16, and treatments are currently limited.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.