Comprehensive Whole-Genome Resequencing Unveils Genetic Diversity and Selective Signatures of the Xiangdong Black Goat

March 2024 in “ Frontiers in genetics ”

Z. A. Liu, Li Haobang, Yang Luo, Jianbo Li, Ao Sun, Zulfiqar Ahmed, Baizhong Zhang, Chuzhao Lei, Kangle Yi

hair growth genetic diversity selective signatures SNPs selective sweep genes reproduction immunity lactation thermoregulation

TLDR Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.

This study conducted whole-genome resequencing on 20 Xiangdong black goats and 139 samples from six other Chinese goat breeds to explore their genetic diversity and selective signatures. The analysis identified 19,133,125 SNPs, mostly in intergenic and intronic regions, and revealed that Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and a substantial effective population size. Population structure analysis showed reduced genetic differentiation compared to some breeds but greater divergence from Jining goats. Selective sweep methods identified genes related to reproduction, immunity, lactation, hair growth, and thermoregulation. These findings provide valuable insights for breeding and conservation programs.

View this study on frontiersin.org →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

Whole-Genome Sequencing of Eight Goat Populations for the Detection of Selection Signatures Underlying Production and Adaptive Traits

research Whole-Genome Sequencing of Eight Goat Populations for the Detection of Selection Signatures Underlying Production and Adaptive Traits

92 citations, December 2016 in “Scientific Reports”

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Related Community Posts Join

6 / 1000+ results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 1 month ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community How uninformed the general public is about hair loss

in Chat 319 upvotes 8 months ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2597 upvotes 2 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

in Technology 106 upvotes 1 year ago

The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

community Recently went bald and will stop taking finasteride. Will stop taking it impact density in my beard and eyebrows? Also here’s after and before picture

in Shaved/buzzed 107 upvotes 1 month ago

The user recently went bald and plans to stop taking finasteride, questioning its impact on beard and eyebrow density. Responses suggest he looks good both bald and with thinning hair, with some recommending minoxidil for the crown and noting finasteride's effect on beard thickness.

community Balding, short, small penis. What is the point of living…

in Treatment 405 upvotes 3 years ago

A 24 year old male struggling with the physical and mental effects of balding, being short, and having a micropenis. Suggested treatments include taking medications such as finasteride and minoxidil, lifting weights, and trying not to compare himself to others.

Related Research

1 / 1 results

research Comprehensive Whole-Genome Resequencing Unveils Genetic Diversity and Selective Signatures of the Xiangdong Black Goat

March 2024 in “Frontiers in genetics”

Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.