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The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Belimumab effectively controls SLE disease activity and reduces steroid use.

Blocking β-catenin in skin cells improves hair growth during wound healing.

AGA is a common hair loss disorder, and early diagnosis and treatment with minoxidil or finasteride can help reduce emotional distress.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

North American ginseng extract helped regrow hair in balding mice.

Hair follicle stem cells could be used to treat the skin condition vitiligo.

3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.

SCAD can indicate ANA-negative lupus, especially in women with unusual symptoms.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

Skin aging reflects overall body aging and can indicate internal health conditions.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.

PRP heals pockmarked skin better than salmon DNA serum.

Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.

New cancer treatments aim to reduce side effects and improve effectiveness.

Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.

Secondary syphilis in Cali, Colombia, shows high Treponema pallidum presence and challenges in early diagnosis, needing better public health strategies.

Chronic cutaneous lupus erythematosus causes scarring, hair loss, and skin discoloration, especially on sun-exposed areas.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Zinc is effective for treating various skin conditions, including warts and acne.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Nanoemulgel is a better way to deliver drugs through the skin for various conditions.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.