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420-450 / 1000+ resultsresearch LINCS Dataset-Based Repositioning of Dutasteride as an Anti-Neuroinflammation Agent
This study reported that dutasteride, identified through a drug repurposing strategy, showed the potential to reduce neuroinflammation and cognitive impairment in LPS-stimulated models.
research Comparative analysis of low-dose oral minoxidil with spironolactone versus finasteride or dutasteride in female androgenetic alopecia management
Both treatment combinations improved hair growth similarly and were safe.
research Farmácia do Lago, Porto e nos Serviços Farmacêuticos do Nemocnica Akademika Ladislava Dérera (Kramáre Hospital), Eslováquia
This study consisted of a pharmacy master's thesis detailing practical experiences during a hospital and community pharmacy internship and scientific investigations into the off-label use of dutasteride for androgenetic alopecia and oral vaccines for urinary tract infection prophylaxis, emphasizing therapeutic applications and mechanisms of action.
research Enhanced effect of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles on hair growth
In this study, applying FGF-2-containing dalteparin/protamine nanoparticles to the scalp was associated with a significant increase in hair diameter over six months among participants with thin hair.
research Investigation of the Mitigation of DMSO-Induced Cytotoxicity by Hyaluronic Acid following Cryopreservation of Human Nucleus Pulposus Cells
In this study, human nucleus pulposus cells treated with hyaluronic acid showed increased proliferation and reduced oxidative stress compared to those treated with EDTA-PBS, suggesting a potential role for hyaluronic acid in enhancing intervertebral disc therapy.
research 15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth
This study found that 15-dPGJ2 promotes apoptosis in human follicular keratinocytes, suggesting its potential role in developing hair loss prevention treatments through DP2 antagonism.
research Monthly versus quarterly dutasteride mesotherapy for male androgenetic alopecia: A randomized trial
research Therapeutic Application of Microsponges-based Drug Delivery Systems
This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
research Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
This study found that several compounds from Yangxue Shengfa capsule may promote hair growth by enhancing cell proliferation in vitro, suggesting potential use in treating androgenetic alopecia.
research Development and Characterization of Dutasteride Bearing Liposomal Systems for Topical Use
This study found that a dutasteride-loaded liposomal system significantly increased skin permeability and drug deposition in mouse skin compared to other formulations, suggesting improved localized treatment potential for androgenetic alopecia.
research 560 The molecular mechanism of PCE-DP, a novel brightening active ingredient
This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.
research Voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP)-modified carbon paste electrode
This study developed and optimized a molecularly imprinted polymer-based electrochemical sensor, demonstrating its ability to detect minoxidil with high sensitivity and selectivity at concentrations as low as 0.3 nM, and successfully applied it for minoxidil measurement in various real sample matrices.
research Prednisolone
A woman's hair grew back after she stopped taking the Parkinson's disease medication pramipexole.
research [Finasteride--ris of "unintentional doping"].
research Synthesis of minoxidil conjugates and their evaluation as HL-60 differentiation agents
This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.
research A narrative review of therapies for scalp dermatomyositis
This review summarizes treatments for scalp involvement in dermatomyositis and suggests that therapies like low-dose naltrexone and platelet-rich plasma may warrant further investigation, although evidence remains limited.
research Study of the interaction between self-assembling peptide and mangiferin and in vitro release of mangiferin from in situ hydrogel
RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
research Finasteride Attenuates Pathological Gambling in Patients With Parkinson Disease
Finasteride reduces gambling symptoms in Parkinson's patients.
research Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
In this study, withdrawal from progesterone and treatment with finasteride were associated with increased signs of depression-like behavior in female mice, suggesting decreased allopregnanolone levels may play a role.
research Dexpanthenol may be a novel treatment for male androgenetic alopecia: Analysis of nine cases
In this study, nine male cases of androgenetic alopecia showed marked improvement after receiving systemic dexpanthenol treatment.
research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.
research Treating Psoriasis: What Is New About Fumaric Acid Esters?
This meeting review discusses recent advances in systemic psoriasis treatments, emphasizing the impact of dimethylfumarate monotherapy on understanding psoriasis and treatment strategies; it reports no new clinical results.
research Development of polymeric nanoparticles containing dutasteride for treatment of androgenic alopecia
This study developed polymer nanoparticles with and without chitosan coating to deliver dutasteride to hair follicles for treating androgenic alopecia. Both nanoparticle types showed controlled drug release and enhanced follicle targeting, especially with mechanical stimulus, supporting their potential as effective topical carriers in skin layers.
research Characterization of Soluplus/ASC-DP Nanoparticles Encapsulated with Minoxidil for Skin Targeting
This study found that Sol/ASC-DP nanoparticles could enhance the skin permeability of minoxidil due to improved stability and hydrophobic interactions in the nanoparticle structure.
research The Efficacy of Topical Dapsone in Lichen Planopilaris with Beard Involvement: Potential Role for Neutrophil Involvement in Pathogenesis
In this study, researchers reported that applying topical 7.5% dapsone led to a significant decline in lichen planopilaris activity within a month and a sustained two-year remission in a patient intolerant to other treatments, suggesting dapsone as a promising alternative for managing this condition.
research Control of lice infestation in horses using a 10 mg/mL deltamethrin topical application
In this study, a single application of a 10 mg/mL deltamethrin-based solution effectively reduced lice infestations by 98% to 100% in treated horses and prevented new infestations for up to a month, without adverse events reported.
research Prostaglandin D2(PGD2); prostaglandin D2 receptor (CRTH2; GPR44; CD294); prostaglandin D2 synthase (PTGDS)
Blocking a protein called prostaglandin D2 might help treat hair loss.
research Porcine acellular dermal matrix facilitates hair follicle stem cells entering the hair cycle in C57/BL6 mice
In this study, porcine collagen acellular dermal matrix scaffolds combined with mice platelet-rich plasma were associated with increased hair density and follicle regeneration in mice with alopecia, suggesting a potential therapeutic approach.