4 citations
,
August 2022 in “Cells” This study found that the lncRNA lncRNA2919 is involved in hair follicle regeneration by downregulating growth-related genes, inhibiting cell proliferation, and promoting apoptosis in rabbit dermal papilla cells.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” This study suggests that 5-ADIOL-S may contribute to the synthesis of potent androgens in peripheral tissues, and 3 alpha-DIOL-S could be a marker of androgen metabolism in various female patient groups.
December 2025 in “Zagazig University Medical Journal” This review discusses polydioxanone threads as a promising, minimally invasive treatment for androgenetic alopecia in both males and females, but notes that further research is needed to optimize protocols and outcomes.
11 citations
,
February 2020 in “Dermatology and therapy” This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
7 citations
,
August 2021 in “Pharmaceutics” This study explored the use of dexamethasone-loaded polymer hybrid nanoparticles in a xanthan gum hydrogel for treating alopecia areata, finding that freeze drying with sucrose influenced particle size, release, and permeation, but had no impact on cytotoxicity or anti-inflammatory efficacy in human keratinocytes.
July 1999 in “Journal of the American Academy of Dermatology” This review discusses valproic acid as a common antiseizure medication associated with alopecia and highlights the need for its inclusion in relevant medical guides, without presenting new clinical findings.
May 2026 in “BMC Medicine” This study found that ACOD1 deficiency in dermal papilla cells promotes mitochondrial dysfunction and contributes to cellular senescence in androgenetic alopecia, suggesting ACOD1 as a potential therapeutic target and 4-octyl itaconate as a promising treatment option for AGA.
98 citations
,
February 2010 in “Dermatology Online Journal” This article outlines the potential for upregulating the vitamin D receptor in treating hair disorders, emphasizing the need for further studies to evaluate vitamin D's role in the hair cycle.
9 citations
,
August 2018 in “Biomedical dermatology” This study found that topical administration of the TGFβ mimetic peptide DPS-1 stimulated hair growth in mice by promoting HDP cell proliferation and enhancing hair follicle morphology.
2 citations
,
February 2023 in “Anais Brasileiros de Dermatologia” 2 citations
,
March 2019 in “PubMed” This report presents the early development of the Lupus Foundation of America's LFA-REAL™ patient-reported instrument, designed to enhance evaluation of lupus disease activity by combining patient and physician assessments.
6 citations
,
January 2020 in “Skin Pharmacology and Physiology” This study demonstrated that caffeine, minoxidil, and the HIF-1α-stimulating agent deferiprone significantly enhanced dermal papilla cell proliferation in a 3D culture model, suggesting deferiprone as a potential alternative to minoxidil.
January 2026 in “Mendeley Data” This study provides supplementary materials detailing the dosing and adverse effects associated with combination oral spironolactone and low-dose oral minoxidil for hair loss in adult females but reports no new clinical findings.
February 2023 in “Archives of Dermatological Research” This study found fractional carbon dioxide laser therapy effective in treating alopecia areata, both alone and with topical treatments, suggesting decorin's involvement in improving hair growth.
3 citations
,
May 2024 in “International Journal of Dermatology”
January 2020 in “International Journal of PharmTech Research” This case report describes a patient with untreated lepromatous leprosy developing Lucio's phenomenon, highlighting difficulties in distinguishing it from erythema nodosum leprosum with vasculonecrotic lesions.
January 2025 in “International Journal of Biological Macromolecules” This study found that decorin treatment significantly enhances dermal papilla cell proliferation, promoting hair follicle growth by influencing the SMAD3/TGF-β signaling pathway through exosomal miR-129–2-3p, which may aid in novel strategies for treating hair disorders and enhancing wool production.
37 citations
,
May 2016 in “JAAD case reports” This abstract describes monilethrix, an autosomal dominant genodermatosis with symptoms like hair fragility and keratosis pilaris, and does not report new experimental results.
36 citations
,
March 2014 in “Annals of the Rheumatic Diseases” This study found that activating liver X receptors with an agonist reduced skin fibrosis in experimental models, particularly in inflammation-driven conditions, by inhibiting macrophage infiltration and interleukin-6 release.
26 citations
,
March 2015 in “American journal of clinical dermatology” This study found that systemic mycophenolate mofetil and topical clobetasol were equally effective at reducing lichen planopilaris activity over six months, but satisfaction differed between the treatments.
65 citations
,
October 2015 in “Acta Biomaterialia” This study found that using a pH-sensitive layered double hydroxide nanocarrier to deliver etoposide significantly reduced liver toxicity and enhanced the drug’s effectiveness in targeting and suppressing non-small cell lung cancer.
23 citations
,
March 2021 in “Gels” This study found that minoxidil solubilized in gelatin-containing microemulsions resulted in over 5% of the drug remaining in porcine skin, significantly more than the reference gel.
This article reviews approved treatments for androgenetic alopecia and reports no new research findings, highlighting the need for further studies.
45 citations
,
July 2002 in “The Neurologist” This article reviews the challenges of using disease-modifying therapy for multiple sclerosis and offers strategies to improve treatment adherence and manage adverse effects, but reports no new clinical findings.
September 2025 in “JMIR Dermatology” This narrative review reported that direct-to-consumer teledermatology improves access to care, adherence, and patient satisfaction for treating male androgenetic alopecia, but may lead to higher drug costs.
31 citations
,
October 2010 in “Progress in lipid research” This review discusses the role of LPA(3) in embryo implantation and its genetic connection with prostaglandin signaling, but reports no new clinical results.
4 citations
,
October 2017 in “International Journal of Applied Pharmaceutics” This study found that hair tonics with 5% and 10% licorice extract promoted hair growth in rabbits similarly to 2% minoxidil and were generally safe, although they caused mild eye irritation at the 2.5% concentration.
15 citations
,
January 1995 in “Archives of dermatological research” In this study, OCT showed strong nuclear binding in certain skin cells, suggesting similar genomic effects to vitamin D with potential therapeutic benefits due to its lower calcaemic effect.
March 2025 in “Journal of the American Academy of Dermatology” Discount pharmacies offer cheaper options for hair loss medications than traditional or direct-to-consumer pharmacies.
6 citations
,
August 2024 in “Biomacromolecules” This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.