April 2023 in “Dermatology practical & conceptual” This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.
June 2026 in “International Journal of Advanced Multidisciplinary Research and Studies” This study highlights the potential of a ketoconazole antifungal hair spray as an innovative and effective topical method for treating tinea capitis, offering benefits such as easy application, improved drug penetration, and reduced systemic exposure compared to conventional treatments.
February 2013 in “Journal of The American Academy of Dermatology” Finasteride solution helps treat hair loss.
September 2024 in “Journal of the American Academy of Dermatology” This study found that a new compounded topical solution for alopecia was clinically tolerable and did not cause irritation, while also showing potential to enhance hair growth through fibroblast proliferation and gene expression.
19 citations
,
November 2011 This review discusses the topical use of systemic drugs for cutaneous disorders and reports a lack of strong evidence from randomized controlled trials, highlighting the need for larger comparative effectiveness studies.
22 citations
,
March 1999 in “International Journal of Clinical Practice” This review discusses the use of topical immunotherapy for severe alopecia areata and resistant viral warts, highlighting diphencyprone's advantages and the need for careful handling to avoid staff sensitisation; it reports no new clinical results.
50 citations
,
July 2014 in “International Journal of Clinical Pharmacology and Therapeutics” This study found that both topical and oral finasteride significantly reduced plasma DHT after one week, with lower finasteride plasma exposure for the topical formulation.
14 citations
,
July 2021 in “Journal of the American Academy of Dermatology” Topical dapsone gel reduced flare-ups in folliculitis decalvans without side effects.
January 2020 in “Veterinary world/Veterinary World” This study found that a topical solution of essential oils, plant-extracted polyunsaturated fatty acids, and Vitamin E improved hair shine, reduced flaking and hair loss, and enhanced skin hydration in rabbits with skin issues.
1 citations
,
October 2023 in “Indian dermatology online journal” This study reviewed the use of various common household items as home-based remedies for dermatological conditions, noting their popularity due to accessibility, cost-effectiveness, and cultural acceptance, but underlined the need for more rigorous studies to establish their evidence-based efficacy compared to conventional treatments.
42 citations
,
December 2015 in “International Journal of Clinical Pharmacology and Therapeutics” This study found that applying a novel 0.25% finasteride solution to the scalp can effectively reduce scalp DHT levels in men with androgenetic alopecia, potentially reducing systemic side-effects.
January 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study concluded that topical betamethasone valerate lotion is more effective than 15% lactic acid solution for managing multiple patchy alopecia areata over a 12-week period in a sample of 50 patients.
November 2023 in “Dermatology Research and Reports” This study reported that a 1% ivermectin topical cream for rosacea was stable over six months, showing no significant changes in key physical properties or microbial contamination, suggesting it may reduce chronic antibiotic use in rosacea treatment.
October 2018 in “Springer eBooks” The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.
9 citations
,
January 2017 in “Organic Process Research & Development” This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.
13 citations
,
November 2017 in “BMC Veterinary Research” This study suggests that topically applied fusidic acid may penetrate only the most superficial layers of canine skin but can reach sufficient concentrations to potentially treat infections caused by pathogenic staphylococci.
July 2026 in “Dermatology Reports” In this pilot study, a medical device gel with hyaluronic acid and hydrogen peroxide showed promising safety and clinical performance for treating folliculitis in adults, reducing lesion count and improving severity scores and quality of life over 8 weeks.
19 citations
,
January 2022 in “Journal of Nanomaterials” This study concluded that an adapalene nanohydrogel containing Tween-80 could be a promising and stable topical treatment option for acne vulgaris due to enhanced skin permeability and stability compared to other formulations.
December 2025 in “JEADV Clinical Practice” This review reports that innovative topical treatments for dermatologic conditions like acne and atopic dermatitis show minimal systemic absorption, indicating improved safety and tolerability compared to traditional therapies.
3 citations
,
October 2013 This study found that microemulsion and microemulsion-based hydrogels may offer a more effective and sustained topical delivery method for minoxidil compared to conventional solutions for hair loss treatment.
6 citations
,
August 2019 in “Indian drugs” This review discusses ethosomal delivery systems for topical drugs, highlighting their potential to improve treatment efficacy for conditions like herpes labialis and male pattern baldness, and reports no new clinical results.
April 2017 in “Journal of Investigative Dermatology” This study found that 10% carbamide peroxide significantly reduced acne lesions compared to a vehicle solution, suggesting it as an effective and safe alternative to benzoyl peroxide for treating mild to moderate acne.
1 citations
,
June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.
5 citations
,
January 2020 in “Veterinary Dermatology” In this study, researchers evaluated the antifungal effectiveness of topical products on infected kitten hair, finding most were effective after one application, with enilconazole and lime sulfur showing residual activity; however, 0.15% ketoconazole with chlorhexidine had no such lasting effect.
February 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study concluded that topical betamethasone valerate lotion is more effective than topical 15% lactic acid solution for managing multiple patchy alopecia areata over a 12-week treatment period.
September 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that topical rosemary solution was as effective as Minoxidil 2% in treating alopecia areata on the scalp.
13 citations
,
July 2016 in “Veterinary Dermatology” In this study on dogs, topical antimicrobial sprays with varying ingredient profiles showed different levels of S. pseudintermedius growth inhibition, maintaining activity for at least 10 days.
123 citations
,
February 2002 in “Journal of The American Academy of Dermatology” Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.
4 citations
,
January 2023 in “Skin Pharmacology and Physiology” This study observed that an ointment containing pine turpentine oil, larch turpentine, and eucalyptus oil showed significant improvement over placebo in lesion evolution, responder rates, and patient assessments for treating acute folliculitis, while being well-tolerated across treatments.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.