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Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

More hair loss leads to higher risk of psychosexual disorders, especially in women.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

The document explains the genetic causes and characteristics of inherited hair disorders.

Chicken feather gene mutation helps understand human hair disorders.

Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.

Adults with polycystic ovary syndrome are much more likely to have obstructive sleep apnea.

SHBG may be a useful early indicator and treatment target for PCOS.

A new gene variant in the DSP gene is linked to a unique type of hair loss.

Adrenal disorders can cause lasting brain and behavior issues in children.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Vitiligo is underreported in medical claims and is linked to certain skin types and autoimmune diseases.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.