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A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.

Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

Wound healing is complex and requires more research to enhance treatment methods.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Middle-aged skin shows aging signs, and quercetin might help delay them.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Notch signaling disruptions can cause various skin diseases.

The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.

BMI is not a significant predictor of complications after gender-affirming penile inversion vaginoplasty.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

New therapies are being developed that target integrin pathways to treat various diseases.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.