Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the therapeutic potential of adipose-derived stem cells compared to other mesenchymal stem cells, emphasizing their promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, but reports no new clinical results.

This study reports that a lower 2D:4D finger length ratio is significantly associated with higher disease activity and reduced spinal mobility in females with ankylosing spondylitis, but not in males.

This review outlines guidelines for designing Janus hydrogel bioadhesives, highlighting their potential to enhance clinical applications in tissue repair and regenerative medicine by mimicking natural biological barriers, although challenges remain in optimizing their asymmetric surface designs.

This report presents a rare case where a patient with chronic urticaria developed alopecia areata during azathioprine therapy, accompanied by bone marrow suppression; these effects resolved after stopping the medication, suggesting a possible link between azathioprine and autoimmune activation despite its intended immunosuppressive use.

This study suggests that gendered social factors, in addition to biological differences, contribute significantly to sex disparities in adverse drug event reports, with patient and event type influencing observed differences.

This study identifies a new mutation in the Scd1 gene in a strain of Kunming mice, causing skin and hair defects with the mildest impact among similar mutations.

In this laboratory study, finasteride administration in male rats lowered dihydrotestosterone levels and reduced c-Fos protein activation in brain tissue, indicating an impact on brain regions like the hippocampus, though these effects diminished after one month of withdrawing the drug.

Dupilumab may cause hair loss in some patients with severe atopic dermatitis.

This study found that deleting Snai2 and Snai3 genes in mice disrupts immune cell development, resulting in severe autoimmunity and early death due to the loss of immune tolerance.

This study found that adipose-derived exosomes may inhibit adipogenesis and lipogenesis in adipose-derived stem cells by activating Hedgehog signaling, suggesting potential applications for improving wound healing in obesity.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

This article presents a case of a seventeen-year-old female with dermatopathia pigmentosa reticularis and emphasizes the importance of distinguishing its clinical features from other similar disorders, supported by dermoscopic and histopathological findings.

This study suggests that targeting the increased expression of SIX1 in systemic sclerosis may be a viable strategy for addressing dermal fibrosis.

This research found that immobilizing type I atelocollagen onto artificial hair significantly improved the adhesion and long-term fixation of the hairs in the human scalp, indicating high biosafety and enhanced tissue integration.

This report presents a case of acrodermatitis enteropathica in a 22-year-old female, highlighting the absence of underlying comorbid conditions.

This study found that mice lacking syndecan-1 experienced cold stress and metabolic issues due to reduced intradermal fat, which was restored by thermoneutral housing or rosiglitazone treatment.

This review discusses the diagnostic criteria and guidelines for managing loose anagen syndrome and differentiating it from non-scarring alopecias, but it reports no new clinical results.

In this study, a group taking compound ginseng cicada decoction showed significantly lower relapse rates, severity, and itching related to atopic dermatitis over 3 months compared to a control group, and reported improved quality of life with no significant adverse events.

This study found that adipose derived stem cells in areas of alopecia in patients with androgenetic alopecia showed different levels of various signaling proteins compared to other scalp and periumbilical regions.

This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.

This case report describes a newly identified condition called loose anagen hair of childhood, characterized by easily pluckable hair in two young boys, with variable duration and no scalp inflammation or scarring.

This study reported that dermatological adverse events are common in patients treated with amivantamab for non-small cell lung cancer, often impacting quality of life and requiring treatment modifications.

This study found significant differences in enrollment and completion rates among racial and ethnic groups in alopecia areata clinical trials, with Black patients showing lower enrollment and higher dropout rates compared to other groups.

This study found that androgen deprivation therapy is associated with an increased risk of acquired long-QT syndrome and Torsades de Pointes, particularly highlighting enzalutamide's greater association with sudden death compared to other therapies.

This study analyzed safety data for semaglutide, liraglutide, and tirzepatide from the EudraVigilance database, identifying potential safety signals not listed in current SmPCs, such as optic ischemic neuropathy and pancreatitis, underscoring the importance of ongoing pharmacovigilance.

In this study, Smad4 deletion in satellite cells hindered skeletal muscle regeneration in adult mice and did not enhance regeneration in aged mice, indicating Smad4's crucial role in muscle repair.

This study found that inducing a leaky gut in mice led to increased gut permeability and decreased expression of protective genes, suggesting a potential link to alopecia areata.

In this study, three patients with alopecia areata exhibited spotty absence of the whiteness of their nail lunulae, potentially due to defects in the matrical epithelium.