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The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Minoxidil boosts enzymes that help hair growth.

Trichoscopy can effectively tell apart tinea capitis and alopecia areata in children by looking for specific hair shapes.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.