research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
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research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function
The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
research The Scientific Legacy of Stephen Rothman
Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
research Placental Extracts, Proteins, and Hydrolyzed Proteins as Active Ingredients in Cosmetic Preparations for Hair Loss: A Systematic Review of Available Clinical Evidence
Placenta products might help with hair loss, but more research is needed.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Cortexolone 17α-Propionate (Clascoterone) Is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro
Clascoterone may be an effective topical treatment for hair loss.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research DHT and E2 Synthesis-Related Proteins and Receptors Expression in Male Yak Skin During Different Hair Follicle Stages
Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase
Glioblastoma cells can make androgens, which might help the tumor grow.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research The Effect of Finasteride and Dutasteride on the Synthesis of Neurosteroids by Glioblastoma Cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research Homocysteine in Androgenetic Alopecia: A Case Control Study and Observational Experiments on Mice
Higher homocysteine levels may inhibit hair growth and are linked to androgenetic alopecia.
research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
research Thyroid Receptor β: A Promising Target for Developing Novel Anti-Androgenetic Alopecia Drugs
Thyroid receptor β can help develop new drugs to treat hair loss.
research A Review of the Treatment of Male Pattern Hair Loss
Finasteride and minoxidil work best together for hair loss.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Efficacy of a Nutritional Supplement Standardized in Fatty Acids and Phytosterols on Hair Loss and Hair Health in Both Women and Men
The nutritional supplement improved hair quality and reduced hair loss.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Defining MicroRNA Signatures of Hair Follicular Stem and Progenitor Cells in Healthy and Androgenic Alopecia Patients
Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
research Review of the Effects of 17α-Estradiol in Humans: A Less Feminizing Estrogen with Neuroprotective Potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Clinical, Trichoscopic, and Folliscopic Identification of the Impact of Metabolic Syndrome on the Response to Intradermal Dutasteride 0.02% Injection in Patients with Female Pattern Hair Loss: A Prospective Cohort Study
Metabolic syndrome reduces effectiveness of hair loss treatment.
research Androgenetic Alopecia Present in the Majority of Patients Hospitalized with COVID-19: The 'Gabrin Sign'
Most COVID-19 patients in hospitals have androgenetic alopecia, more in men, suggesting a link between androgen sensitivity and severe COVID-19 symptoms.