1 citations
,
June 2025 in “Scientific Reports” In this study on testosterone-induced benign prostatic hyperplasia in rats, hydroxychloroquine significantly reduced prostate-related markers and enhanced therapeutic effects when combined with finasteride, suggesting potential as a new treatment approach.
7 citations
,
April 2009 in “Bioorganic & Medicinal Chemistry Letters” Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
29 citations
,
November 2021 in “FEBS Open Bio” In this study, molecular docking simulations and cell-based assays suggested that certain analogues of cepharanthine might possess anti-SARS-CoV-2 activity.
6 citations
,
May 2023 in “Molecules” In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.
7 citations
,
August 2020 in “Majalah Farmasetika” This review concluded that a herbal hair tonic formulated with 2.5% green tea leaf extract, in combination with specific solvents and additives, showed the best properties for stimulating hair growth.
16 citations
,
October 2007 in “Andrologia” This study suggests that DHT may have a less potent effect on the prostate compared to testosterone while maintaining safety and similar effects on erythropoiesis and lipids.
53 citations
,
December 2012 in “Revista da Sociedade Brasileira de Medicina Tropical” In this study, liver transaminase levels and various symptoms persisted in some adult dengue patients even two months after diagnosis.
1 citations
,
October 2015 in “Interest : Jurnal Ilmu Kesehatan” In this study, both gel and microemulsion formulas containing waru leaves and Java Tamarind extracts were found to have similar in vivo hair growth activity in rabbits.
This review discusses the potential use of Adiantum capillus-veneris extract for COVID-19 symptom management and reports no clinical findings, highlighting a need for trials to evaluate its efficacy.
This study found that the optimized topical AR antagonist 39, derived from 14-P1, demonstrated potent AR antagonism and comparable efficacy to pyrilutamide in a hair-growth mouse model, with a faster onset and favorable safety profile.
January 2013 in “Dépôt Institutionnel de lUniversité de Tlemcen” This study observed that extracts from Ficus carica may temporarily increase blood glucose levels before returning to normal in diabetic rats, while Citrullus colocynthis extracts demonstrated an antihyperglycemic effect but had potential toxicity at higher doses.
15 citations
,
July 2009 in “Biomedical Chromatography” This study developed and validated a sensitive liquid chromatography–mass spectrometry method to measure aristolochic acid‐I in rat plasma, successfully applying it to pharmacokinetic research.
2 citations
,
February 2018 in “International Research Journal of Pharmacy” This study reported that an alkaloid isolated from E. alba leaves inhibited HIV-1 reverse transcriptase activity with minimal cytotoxicity, suggesting its potential as an antiviral agent.
6 citations
,
October 2016 in “Food Science and Biotechnology” This study found that the water extract of Bituminaria bituminosa demonstrated the highest antioxidant activity and α-glucosidase inhibition among tested extracts, but no cholinesterase or tyrosinase inhibition.
4 citations
,
August 2022 in “The Scientific World Journal” This study found that bufotalinin, derived from Merremia peltata leaves, may enhance hair growth by acting as a potential androgen receptor antagonist in rabbits.
In this study, a dual soft drug design strategy improved the AR antagonist candidate 39, showing potent AR antagonism and good safety in a mouse hair-growth model, with similar efficacy to pyrilutamide but faster response.
66 citations
,
July 2005 in “Journal of pediatric gastroenterology and nutrition” This case report describes acute liver injury in a 5-year-old Caucasian girl after ingesting the Chinese herbal product Shou-Wu-Pian, suggesting a potential link between this unregulated herbal remedy and hepatotoxicity.
November 2022 in “PLANT ARCHIVES” This study reported on 23 medicinal plant species used in Ben M'hidi, El-Tarf, Algeria, providing ethnobotanical insights into their traditional therapeutic applications.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study evaluated formulations of a cream containing turmeric and ginger extracts for inhibiting underarm hair growth, finding that the formulation with 15% stearic acid and 3% triethanolamine had the most optimal physical characteristics and potential for cosmetic development.
October 1977 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” This study found that telogen effluvium occurred in two subjects taking 500 mg of mefloquine weekly, and gastrointestinal intolerance was observed at higher doses in additional acute studies.
October 2025 in “Influenza and Other Respiratory Viruses” This study found that bis-benzylisoquinoline and Amaryllidaceae alkaloids, especially aromoline, show potential as antiviral agents, suggesting they could serve as foundations for developing new treatments against coronaviruses by enhancing the understanding of their structure-activity relationships.
165 citations
,
July 1992 in “Annals of Internal Medicine” This editorial discusses the potential health risks of herbal preparations, highlighting a case of hepatotoxicity in a child due to pyrrolizidine alkaloids in a herbal tea; it reports no new results.
1 citations
,
January 2019 This study found that a hair tonic combining fragrant pandan and celery extracts increased hair length in guinea pigs, with the 1:5 concentration showing the best growth activity.
This study assessed the phytochemical properties and antifungal activity of Lawsonia inermis extracts, finding diverse compounds like flavonoids and alkaloids, and reporting that ethanol extracts exhibited the highest antifungal activity against Aspergillus flavus and Candida albicans at 200 mg/mL.
September 1978 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This review discusses the antimicrobial and protective effects of hesperidin and hesperetin against various toxicities, with potential mechanisms explored, but it reports no new research findings.
6 citations
,
June 2022 in “Journal of Clinical Medicine” This study found that for men with moderate-to-severe LUTS/BPH, 6 months of treatment with tamsulosin plus the hexanic extract of S. repens was as effective as tamsulosin plus a 5-alpha-reductase inhibitor but had better tolerability.
In this case report, interferon-alpha treatment for a man with hemophilia and hepatitis C was associated with unexpected diffuse hair growth, likely caused by the medication.
2 citations
,
November 2023 in “International Journal of Preventive Medicine and Health (IJPMH)” This study explored the effects of a 50% hydroalcoholic UPBF extract on BPH in testosterone propionate-induced rats, finding significant improvements in prostate-related parameters and lower urinary tract symptoms at a 200 mg/kg dose, suggesting potential use in BPH management.
In this study, the researchers reported that the optimized compound 39 demonstrated potent AR antagonism and favorable pharmacokinetics in a hair-growth mouse model, achieving similar efficacy to pyrilutamide with faster onset and preserved safety, offering promise for next-generation topical AR antagonist development.
26 citations
,
September 2018 in “Neurobiology of Disease” This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.