October 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study reviewed existing literature on Androgenetic Alopecia treatments, finding that minoxidil promotes hair growth but can cause side effects due to its traditional formulations. Novel delivery systems like film-forming sprays may reduce these side effects and enhance efficacy.
46 citations
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May 2003 in “Mechanisms of Development” This study found that overexpression of the calcium sensing receptor in transgenic mice accelerates epidermal differentiation and hair growth, suggesting its role in enhancing calcium signaling and interaction with other pathways.
30 citations
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September 2009 in “Seminars in Cutaneous Medicine and Surgery” This review outlines how dermoscopy enhances diagnostic accuracy by up to 30% compared to unaided visual inspection and explores its potential as a research tool without presenting new research findings.
20 citations
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January 2003 in “Journal of oleo science” This study found that both everyday physical and environmental stresses, as well as chemical treatments, contributed to hair damage, with cuticle layers being more noticeably affected.
19 citations
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June 2020 in “International Journal of Dermatology” In this systematic review, oral minoxidil was found to be a safe and effective treatment for androgenetic alopecia and alopecia areata, with additional benefits for female pattern hair loss and other types of alopecia, although common side effects included hypertrichosis and postural hypotension.
7 citations
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May 2014 in “Clinical practice” This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.
4 citations
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May 2022 in “Future Journal of Pharmaceutical Sciences” This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.
3 citations
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October 2014 in “Pharmaceutical Development and Technology” This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.
2 citations
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April 2024 in “Cosmetics” This study investigated non-laser methods for removing permanent makeup using plant extracts, testing their decolorization effects on mice through tattooing and electroporation techniques.
2 citations
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August 2016 in “Lasers in Surgery and Medicine” In this study, photodynamic therapy was found to achieve permanent reduction of nonpigmented hair in mice, unlike an 800-nm diode laser, by targeting the hair matrix through repeated sessions.
1 citations
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December 2022 in “Middle East Journal of Science” This review covers hair dye formulations, their mechanisms, and potential applications, but reports no new findings; the authors highlight the process of oxidative dyeing and repairing damaged hair.
September 2023 in “International Journal of Applied Pharmaceutics” This study found that a topical gel containing Minoxidil and Tofacitinib citrate showed promise for treating alopecia areata, with formulation F5 demonstrating effective drug release and stability in evaluations.
June 2023 in “International Journal for Research in Applied Science and Engineering Technology” This research highlights the potential of emulgel as an advanced topical drug delivery system, offering improved efficacy for hydrophobic medications in treating dermatological conditions and a range of ailments with its dual release control mechanism of gel and emulsion.
November 2021 in “International journal of life science and pharma research” This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.
April 2019 in “Archives of aesthetic plastic surgery” This study evaluated an 808-nm diode laser at different fluences for permanent axillary hair removal in Korean women and found that high-fluence treatment (14 J/cm2) effectively reduced hair density and thickness, with no significant difference in comfort compared to lower fluences.
29 citations
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May 2025 in “Polymers” This study systematically examines how smart biomaterials used with DLP technology can enhance bioprinting in tissue engineering and regenerative medicine, while also identifying current challenges and future research needs.
1 citations
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September 2022 in “F1000Research” This case report describes a 56-year-old man with late-onset systemic lupus erythematosus where digital gangrene was an initial manifestation, highlighting its rarity as a primary sign.
August 2022 in “F1000Research” This case report describes digital gangrene as a rare primary manifestation of late-onset systemic lupus erythematosus in a 56-year-old man, with marked lesion improvement following rituximab treatment.
May 2022 in “Голова и шея.” In this pilot study, researchers observed that low-intensity laser radiation at 445±40 nm increased the temperature of gingival tissues in Wistar rats by 8.37°C without exceeding the safety threshold, suggesting potential for clinical trials.
January 2022 in “Faculty of 1000 Research Ltd” This case report documents digital gangrene as an unusual early sign of late-onset systemic lupus erythematosus in a 56-year-old man, which improved with rituximab treatment.
6 citations
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March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
January 2024 in “Faculty of 1000 Research Ltd” This report describes a case of digital gangrene as an early manifestation of systemic lupus erythematosus in a 56-year-old man, highlighting it as a rare complication of late-onset SLE.
18 citations
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May 2023 in “Science Advances” In this study, transiently activating the sonic hedgehog signaling pathway in chickens transformed reticulate scales on the feet into feathers comparable to body feathers, without ongoing treatment, suggesting this pathway affects the diversity of bird skin appendages.
October 2022 in “Journal of Kermanshah University of Medical Sciences” The researchers reported that caprylic acid effectively enhances the permeability and diffusion of minoxidil through rat skin compared to other penetration enhancers.
205 citations
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January 2005 in “Skin pharmacology and physiology” This review discusses how liposomes and niosomes can enhance drug penetration in topical delivery systems and emphasizes the importance of their specific composition, size, and type, but it reports no new results.
This case study indicates that older patients with NMOSD may show favorable clinical improvements with aggressive treatment, even when the intervention is initiated later in the disease course.
49 citations
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January 2012 in “Dermatology” In this study, only 1 out of 5 patients with anti-TNF-α induced psoriasiform eruptions showed good response to topical treatment, while systemic therapy and discontinuation of anti-TNF-α may prevent scarring alopecia in severe cases.
28 citations
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December 2002 in “Der Hautarzt” TrichoScan accurately measures hair growth and loss, showing increased hair counts and thickness with treatment.
2 citations
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January 2011 in “Lecture Notes in Computer Science” This study presented a hair harvesting robot with an advanced end-effector that improves accuracy and efficiency for Follicular Unit Extraction, showing a precision of 0.014 mm.
June 2025 in “British Journal of Dermatology” In this retrospective study, researchers found that the diagnostic yield for alopecia skin biopsies was lower with longer durations of disease onset and suggested improving diagnostic accuracy through standardized request forms and digital pathology integration.