30 citations
,
April 2017 in “Journal of structural biology” This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.
25 citations
,
June 1990 in “Journal of Pharmaceutical Sciences” This study found that minoxidil absorption through the skin increased with longer contact times, reaching over 75% of the maximum absorption within four hours.
16 citations
,
August 2014 in “Archives of Pharmacal Research” This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.
12 citations
,
January 2012 in “Current Dermatology Reports” This review discusses recent trends in non-surgical cosmetic dermatology procedures in the United States and reports no new clinical results, emphasizing the need for evidence-based evaluations of safety and efficacy.
10 citations
,
November 1984 in “Journal of Colloid and Interface Science” The study found that the Marangoni effect causes the uneven wetting of surfactant-coated hair due to the surfactant moving into the water.
8 citations
,
December 2003 in “Materials Research-ibero-american Journal of Materials” Polyquaternium 7® builds up on hair, improving its look and feel, and AFM is good for measuring these changes.
5 citations
,
August 2014 in “Pharmaceutical Development and Technology” In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.
4 citations
,
January 2019 in “Skin appendage disorders” This study found that Follicular Maps, derived from trichoscopic images, remained consistent over time and unaffected by hair cycling or noncicatricial alopecia, offering a precise tool for diagnosing and monitoring hair and scalp conditions.
4 citations
,
April 1955 in “Textile Research Journal” This study found that the extent of reducing agents' effects on hair fibers was linked to the electrode potential of the reagents used.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
January 2026 in “International Journal of Applied Pharmaceutics” This review discusses the integration of nanoparticles with microneedles to improve drug delivery through enhanced stability, bioavailability, and controlled release, noting ongoing challenges with stability, scalability, and safety.
February 2024 in “Pharmaceutical research” In this in silico study, researchers found that the hair follicle's contribution to dermal permeability of small molecules varies with the lipophilic and hydrophilic properties of substances, highlighting the need for careful characterization of substances filling the follicular route when interpreting experimental permeability data.
June 2023 in “SPIRE - Sciences Po Institutional REpository” This study suggests that extracellular vesicles from prostate cancer cells could aid in identifying tumor heterogeneity and serve as biomarkers, while also playing a role in SARS-CoV-2 infection in nasopharyngeal mucus.
December 2022 in “theses.fr (ABES)” This study found that microplastics on the Lebanese Mediterranean coast transport various organic and inorganic pollutants, posing threats to marine organisms and potentially human health.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that a new model of reconstructed human epidermis using keratinocytes from plucked hair follicles offers a less-invasive alternative to conventional skin-derived models for skin research.
January 2014 in “HAL (Le Centre pour la Communication Scientifique Directe)” This review provides an update on sex hormone-associated dermatoses in dogs, detailing known conditions like feminization syndrome and exploring less understood issues such as alopecia X, without presenting new clinical findings.
January 2014 in “University of the Arts London Research Online (University of the Arts London)” Certain ingredients can help protect hair color.
September 2025 in “Journal of Phytonanotechnology and Pharmaceutical Sciences” This comprehensive review reports on the therapeutic potential and bioactive components of licorice (Glycyrrhiza glabra Linn), highlighting its diverse pharmacological properties and health benefits but also noting associated toxicity and adverse effects in medicinal and food applications.
47 citations
,
June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
46 citations
,
May 2011 in “Movement Disorders” This article contains additional supporting information available online but presents no new research findings.
39 citations
,
May 2011 in “Movement Disorders” Finasteride may help reduce symptoms in male Tourette syndrome patients.
35 citations
,
January 2018 in “Skin pharmacology and physiology” This study found that nanoemulsion formulations with oleic acid or eucalyptol significantly enhanced the delivery and retention of caffeine through hair follicles and surrounding skin regions.
31 citations
,
June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
20 citations
,
December 1995 in “International Journal of Pharmaceutics” Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
17 citations
,
May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
10 citations
,
June 2011 in “Movement Disorders” THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
7 citations
,
June 2011 in “Movement Disorders” A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
5 citations
,
May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
5 citations
,
May 2011 in “Movement Disorders” Finasteride may help reduce tic severity in male Tourette syndrome patients.
4 citations
,
May 2011 in “Movement Disorders” A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.