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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.

Skin aging reflects overall body aging and can indicate internal health conditions.

Epigenetic mechanisms control skin development by regulating gene expression.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Vitamin D Receptor is crucial for normal skin and hair growth.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

EGFR is essential for normal hair development and follicle differentiation.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

S100A3 protein is crucial for hair shaft formation in mice.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Plet-1 protein helps hair follicle cells move and stick to tissues.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Wool follicle cells are more complex than previously thought.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.

circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.

Hair and wool have diverse keratins and keratin-associated proteins.

The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.