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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Targeting colon cancer stem cells might lead to better treatment results.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.

Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Wnt10b helps blood stem cells grow after injury.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.

Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.

N-acetyl-cysteine shows promise in treating various diseases and may improve skin and hair conditions, but more research is needed on dosages and long-term effects.

Hair follicle stem cells need all reprogramming factors to become pluripotent.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

COX2 and ATP synthase control the size of hedgehog spines.

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.