research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
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research Alopecia: Unapproved Treatments or Indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
research Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research Clinical Application of 5α-Reductase Inhibitors
5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
research Inhibition of Steroid 5 Alpha-Reductase with Finasteride: Sleep-Related Erections, Potency, and Libido in Healthy Men
Finasteride doesn't affect erections much, but may decrease libido in men.
research Adverse Effects of Common Medications on Male Fertility
Some common medications can harm male fertility, but many effects can be reversed.
research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles
Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
research Human Scalp Hair: Modulation by Various Factors and Hormones - Do Estrogens Inhibit or Stimulate? A Perplexing Perspective
The effects of estrogen on human scalp hair growth are unclear and need more research.
research Differences in Reproductive Toxicology Between Alopecia Drugs: An Analysis on Adverse Events Among Female and Male Cases
Finasteride has a higher risk of reproductive side effects than minoxidil.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Steroid Hormones of Reproduction and Sexual Development
Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
research Androgenetic Alopecia: An Update Of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
research Antiandrogen Therapy for Androgenetic Alopecia
Antiandrogen therapy helps treat genetic hair loss.
research TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Alopecia: Managing the Basics
The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.
research Androgen Excess: Investigations and Management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Androgenetic Alopecia: Update on Etiology
AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
research Diagnosis of Hyperandrogenism: Biochemical Criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
research Obesity and Polycystic Ovary Syndrome: Implications for Pathogenesis and Novel Management Strategies
Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
research The Direct Inhibitory Effect of Dutasteride or Finasteride on Androgen Receptor Activity Is Cell Line Specific
Dutasteride and finasteride affect different cell types differently.
research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota
Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Fortnightly Review: Male Pattern Androgenetic Alopecia
Hair loss in men is common, treatable, but not curable.
research Finasteride Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Ionization Tandem Mass Spectrometry: Application to a Comparative Pharmacokinetics Study
New method measures finasteride in plasma, finds two formulations bioequivalent.
research Signaling Pathways in Hair Aging
Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.