4 citations,
June 2017 in “Endocrine Reviews” Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
4 citations,
July 2001 in “Personality and Individual Differences” Men with moderate hair loss had the best spatial thinking, and long-term DHT might affect cognition.
3 citations,
September 2022 in “Molecules” Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
3 citations,
December 2018 in “Meta Gene” Certain gene variations increase male hair loss risk, influenced by hormone levels.
2 citations,
November 2017 in “Biotechnology Letters” Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
2 citations,
September 1971 in “Metabolism, clinical and experimental” Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.
1 citations,
July 2023 in “Journal of Biophotonics” Red light at 8 mW/cm2 most effectively promotes hair cell growth and affects key growth pathways, especially in cells treated with a hair loss-related hormone.
1 citations,
January 2023 in “The FASEB Journal” CircAGK affects cell death in hair cells by controlling the miR-3180-5p/BAX pathway, which can lead to hair loss.
1 citations,
December 2022 in “Pharmaceuticals” Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
1 citations,
October 2022 in “International journal of endocrinology” Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.
1 citations,
June 2008 in “The Journal of Urology” Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.
1 citations,
January 2008 in “Proceedings of the 9th World Rabbit Congress, Verona, Italy, 10-13 June 2008” Furless male rabbits grew slightly faster and heavier than furred ones, but testosterone levels were not the cause.
December 2024 in “Journal of Biophotonics” Dual wavelength LEDs may help reduce hair loss by lowering DHT levels.
April 2024 in “Journal of ethnopharmacology” Ellagic acid may help regrow hair and prevent hair loss by activating a specific cell growth pathway.
March 2024 in “Cell communication and signaling” Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.
January 2024 in “Biology of sex differences” Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
December 2023 in “International Journal of Applied Pharmaceutics” Moringa seed oil helped hair growth in rabbits, with the highest dose being most effective.
October 2023 in “The Journal of urology/The journal of urology” Higher testosterone and DHT levels are not linked to urinary symptoms in men.
October 2023 in “Journal of the Endocrine Society” A woman's excessive hair growth was linked to a rare case of high testosterone caused by a prolactin-producing pituitary tumor.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
June 2023 in “Clinica Chimica Acta” Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.
February 2023 in “Research Square (Research Square)” Dihydrotestosterone increases arterial stiffness in female mice without changing blood pressure or aortic wall thickness.
January 2023 in “Journal of men's health” Higher dihydrotestosterone may be linked to more inflammation in COVID-19 patients with low testosterone.
October 2022 in “Endocrine journal” Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.
July 2022 in “International Journal of Health Sciences (IJHS) (En línea)” Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.
June 2022 in “Journal of Experimental Biology and Agricultural Sciences” Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.
Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.
January 2003 in “Humana Press eBooks” Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.
March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.