research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
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research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Polycystic Ovary Syndrome and Its Impact on Health
PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
research Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Interventional Studies for Polycystic Ovarian Syndrome in Children and Adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research Bone Morphogenetic Proteins Are Critical Factors for Hair Follicle Epithelial-Mesenchymal Interactions in Androgenetic Alopecia
BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications
The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
research Hirsutism: Diagnosis and Treatment
The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.
research Update: The Pathogenesis and Treatment of Polycystic Ovary Syndrome
New treatments for PCOS focus on managing symptoms and improving fertility.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia
The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Finasteride Does Not Prevent Bladder Cancer: A Secondary Analysis of the Medical Therapy for Prostatic Symptoms Study
Finasteride does not prevent bladder cancer.
research Facile Fabrication of Cedrol Nanoemulsions with Deep Transdermal Delivery Ability and High Safety for Effective Androgenic Alopecia Treatment
Cedrol nanoemulsions effectively treat hair loss by promoting hair growth and reducing DHT levels safely.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Androgenic Effects on Ventricular Repolarization
ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Androgenetic Alopecia: Drug Safety and Therapeutic Strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Thyroid Hormones and Androgens Differentially Regulate Gene Expression in Testes and Ovaries of Sexually Mature Silurana Tropicalis
Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
research Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement
Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.