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Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.

Finasteride and dutasteride effectively reduce DHT in hair, which may help evaluate their treatment success for hair loss.

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Cinnamaldehyde helps bone healing initially but may slow healing later unless combined with DHT treatment.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Mice with human gene experienced hair loss when treated with DHT.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

Treatment during development affects hormone balance and sexual behavior in male rats.

Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.