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This study found that in a mouse model of PCOS, high androgen levels caused pyroptosis in ovarian granulosa cells and increased ER stress in oocytes, reducing oocyte maturation rates, while treatment with CPA and DMF improved these rates.

This narrative review highlights the critical role of intracrine hormone production in peripheral tissues, suggesting that continuous-release subcutaneous testosterone pellet therapy may offer a more effective symptom-driven approach for aging populations, though large-scale randomized controlled trials are needed for confirmation.

In this study, the researchers noted that physicians in China prioritize clinical hyperandrogenism when making PCOS treatment decisions, highlighting a need to align clinical practices with guidance recommendations and to clarify the role of biochemical hyperandrogenism in future guidelines.

Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.

This case report highlights that uncommon ovarian tumors like sclerosal stromal tumors can cause hirsutism and virilization in postmenopausal women and lead to androgen secretion, despite typically being hormonally inactive.

This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.

This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.

This paper reviews seven major systemic causes of hair loss and provides a clinical evaluation framework but reports no new experimental results.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

In this case study, a 71-year-old woman with postmenopausal hirsutism was diagnosed with a Leydig cell tumor and endometrial carcinoma, with hirsutism improving one month after surgery.

This study concluded that serum Adiol-G levels generally parallel testosterone levels and, therefore, do not effectively serve as a marker of peripheral androgen excess in women with androgenic symptoms.

This article provides an in-depth exploration of both natural and synthetic treatments for alopecia, examining their mechanisms, benefits, limitations, and current research, while noting that synthetic therapies can have potential adverse effects.

This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.

This article discusses expert responses to hair loss in women but reports no new research findings.

This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.

This study defined menstrual phase-specific reference intervals for circulating androgen levels in young women, highlighting that anovulatory females showed higher androgen, LH, and FSH levels compared to ovulatory females.

This study found that only eumenorrheic polycystic ovary syndrome patients showed a temporal coupling between kisspeptin and luteinizing hormone pulsatile secretions.

This mini-review discusses the role of androgens, specifically testosterone and dihydrotestosterone, in the pathogenesis of autoimmune liver diseases and reports no new results.

This review examines recent approvals and emerging treatments for androgenetic alopecia, discussing newly approved drugs like Propecia and Rogaine Extra Strength 5%, but without presenting new clinical results.

This review presents substantial evidence supporting testosterone use for hypoactive sexual desire disorder in postmenopausal women, but notes safety concerns with off-label prescribing due to lack of approved formulations.

This review examines age-related changes in androgen levels in women and explores the rationale for testosterone replacement therapy, but it reports no new clinical findings.

This study found that using an oral contraceptive with bicalutamide significantly reduced hirsutism in women with PCOS compared to an oral contraceptive alone, although it increased total cholesterol and LDL levels.

This study found that adrenal hormones appear to inhibit winter fur growth onset in mink and may affect the duration of inactivity between fur growth periods.

This review discusses hypopituitarism's bidirectional relationship with COVID-19 due to metabolic comorbidities and pituitary risks, but it reports no new clinical results.

In this study, BeauTop treatment significantly increased hair growth in people with androgenetic alopecia compared to placebo, showing effectiveness without adverse reactions.

This article discusses the multifactorial nature of acne vulgaris, detailing its link to androgen-induced sebum production, altered keratinisation, inflammation, and bacterial colonisation, but reports no new research findings.

This article discusses the diagnosis and treatment options for hirsutism and reports no new clinical findings.