December 2023 in “Journal of ayurveda and integrated medical sciences” In this case study, a 17-year-old male with patchy hair loss (Indralupta) experienced significant symptom relief after treatment with Pracchanna Karma and Maricha Lepa, suggesting the therapy was effective and economical within a short duration.
April 2025 in “International Journal of Research in Dermatology” This study investigated cutaneous manifestations in thyroid disorder patients, finding that hypothyroid patients commonly experienced dry skin (67.83%) while warm skin (93.3%) and increased sweating prevailed in hyperthyroid patients, with urticaria being the most common autoimmune association among both groups.
2 citations
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January 2020 in “Clinical Dermatology Review” In this study, idiopathic hirsutism was identified as the most common cause of hirsutism among the patients, followed by polycystic ovarian syndrome.
2 citations
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January 2002 This study investigated the pigments and cells causing discoloration in stasis dermatitis but did not clarify the role of melanin or melanocytes in this condition.
42 citations
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September 1985 in “British Journal of Dermatology” This study found that trichothiodystrophic hair shows reduced and disoriented protein deposition in follicles, with both the cuticle and cortex affected, providing localized structural insights into keratin abnormalities.
3 citations
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November 2017 in “PubMed” This study found that individuals with alopecia areata experience variations in cortisol and insulin levels and adaptive mechanism pressures, which may serve as potential therapeutic targets.
May 2026 in “Therapeutic Delivery” This study found that applying a dutasteride-loaded liposome formulation to damp rat skin nearly doubled the drug's follicular accumulation compared to dry skin, suggesting scalp hydration status may significantly impact the drug's topical delivery, especially in follicle-rich areas.
January 2024 in “Genetics in Medicine Open” In this report, two adult patients with Tatton-Brown-Rahman syndrome exhibited new cardiac features, such as atrial fibrillation and ventricular and atrial dilatation, highlighting the importance of cardiovascular follow-up in adults with this condition.
3 citations
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January 2021 in “Veterinary dermatology” This study describes a rare form of congenital alopecia in domestic short hair cats, characterized by hair shaft defects and follicular dystrophy similar to those seen in certain mutant mouse strains.
17 citations
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September 2009 in “British Journal of Dermatology” This study suggests that clinically apparent fragile hair in children is rarely linked to trichothiodystrophy, and the tiger-tail pattern is not wholly specific to this diagnosis.
January 2025 in “Sanjeevani Darshan National Journal of Ayurveda & Yoga” This source examines alopecia areata, an autoimmune condition causing patchy hair loss, describing the current reliance on corticosteroid injections despite their severe side effects, and explores Ayurvedic treatments identified as Shaman and Shodhan for managing an equivalent condition called Indralupta.
13 citations
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April 1994 in “Baillière's clinical endocrinology and metabolism” This review discusses inherited forms of vitamin D-dependent rickets and explains their genetic and metabolic causes but reports no new clinical findings.
June 2026 in “International Journal of Ayurvedic Medicine” The study found that Asthimajjapachak Churna led to greater improvement in managing hair fall among young females compared to Shwadamshtradi Rasayana Churna, particularly through alleviation of Asthigata dosha.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case report details a 29-year-old male with recurrent alopecia areata who achieved complete hair regrowth after five months of Ayurvedic treatments, including Virechan therapy, Shamana Chikitsa, and Jalaukavacharana, with no adverse effects.
June 2024 in “Kerala Journal of Ayurveda” In this case report, an 18-year-old male with alopecia areata showed significant hair regrowth after six weekly treatments with Pracchana, accompanied by the external application of Indraluptha mashi and Malathyadi kera, suggesting these interventions may be effective for managing spot baldness.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this article, the authors discuss Ayurvedic concepts and treatments for Indralupta (Alopecia Areata), highlighting a case successfully managed with Ayurvedic medicine, while contrasting it with modern therapies like corticosteroids and immunosuppressants, which have significant side effects.
4 citations
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October 2021 in “Journal of Clinical Medicine” This study found that individuals with heterozygous truncation-type variants in the *DSP* gene exhibit lower skin temperature and higher transepidermal water loss, with specific microscopic skin changes and pseudomonilethrix.
February 2013 in “Journal of the American Academy of Dermatology” Follicular red dots can appear where alopecia areata and vitiligo overlap.
March 2018 in “Gazi medical journal” This study found that adults with β-thalassemia major had a significantly higher prevalence of skin, hair, and nail disorders compared to healthy controls, influenced by factors like age, gender, and ferritin levels.
2 citations
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September 2016 in “Journal of evolution of medical and dental sciences” This study found that patients with thyroid dysfunction were more likely to experience skin disorders such as chronic idiopathic urticaria, vitiligo, and alopecia areata compared to a control group.
This study highlights the use of dermatoscopy as a valuable tool for diagnosing and monitoring alopecia areata, noting that specific hair shaft alterations such as exclamation-mark hairs and black dots are indicators of active disease, while vellus hairs signal early regrowth.
May 2024 in “Asian Journal of Medical Sciences” This study observed that in patients with primary hypothyroidism, common skin conditions like altered skin texture, dry skin, and diffuse hair loss may emerge before a biochemical diagnosis, suggesting these signs should prompt consideration of hypothyroidism.
December 2016 in “Journal of evolution of medical and dental sciences” This study reported common skin changes and symptoms associated with thyroid disorders, such as dry skin in hypothyroidism and warm, soft skin in hyperthyroidism, and noted urticaria as a frequent autoimmune association in hypothyroid patients.
14 citations
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April 2017 in “Dermatology practical & conceptual” This study reports that yellow dots in a higher number per field of vision were the most consistent dermoscopic finding in severe cases of alopecia areata.
40 citations
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April 2013 in “Dermato-endocrinology” In this study, researchers observed vitamin D insufficiency in many patients with Alopecia Areata, suggesting its potential role in managing this autoimmune condition.
July 2026 in “Journal of Ayurveda and Holistic medicine.” In this case report, a 36-year-old woman with alopecia areata experienced significant clinical improvement, including complete hair regrowth, after undergoing a 60-day Ayurvedic treatment regimen that included Panchakarma procedures and herbal medications.
This study consolidates information on the unique structural and functional biology of Indian hair, reporting distinct scalp microbial ecology and trichoscopic parameters, which are important for diagnosing and treating hair conditions in Indian populations.
10 citations
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May 2018 in “Cell death discovery” This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.
January 2026 in “International Journal of Science and Research (IJSR)” This source discusses ichthyosis, a disorder causing dry, scaly skin, by exploring its genetic causes, potential systemic associations, and treatments, and correlates modern medical insights with Unani medicine principles focused on humoral balance and holistic care.
August 2026 in “International Journal of Versatile Research and Analysis” The study found that a combination of Ayurvedic treatments, including Shamana Aushadhi and Nasya, administered for one month, significantly reduced symptoms such as hair fall, dandruff, itching, and scalp dryness in people experiencing Khalitya Roga (hair loss), with no reported adverse reactions.