Ichthyosis in Unani Medicine: A Comprehensive Review of Disorders of Cornification and Their Modern Dermatological Correlates

    Meenaz Fathima, Sheeraz Fathima
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    Studysummary This source discusses ichthyosis, a disorder causing dry, scaly skin, by exploring its genetic causes, potential systemic associations, and treatments, and correlates modern medical insights with Unani medicine principles focused on humoral balance and holistic care.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The article provides a comprehensive review of ichthyosis, a group of disorders characterized by dry, scaly skin due to impaired epidermal barrier function. It discusses the prevalence, classification, and causes of both inherited and acquired forms, linking genetic mutations to the condition's pathophysiology. Inherited ichthyoses are linked to gene mutations affecting epidermal protein and lipid synthesis, while acquired ichthyosis is associated with systemic conditions. The review correlates traditional Unani medical concepts, such as abnormal black bile and excessive dryness, with modern genetic and metabolic understandings. It also outlines contemporary dermatological and Unani treatment strategies, emphasizing detoxification, humoral balance, and holistic care, showcasing the relevance of Unani medicine in managing ichthyosis alongside modern medical practices.
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