Common Dermatologic Disorders in Down Syndrome: Systematic Review

February 2022 in “ JMIR Dermatology ”

Megan Lam, Justin D. Lu, Levi Elhadad, Cathryn Sibbald, Raed Alhusayen

alopecia areata atopic dermatitis hidradenitis suppurativa ichthyosis psoriasis vitiligo onychomycosis

TLDR People with Down syndrome often have skin issues and need regular check-ups for early treatment.

This systematic review identified an increased prevalence of various dermatologic disorders in patients with Down syndrome (DS), including atopic dermatitis, hidradenitis suppurativa, ichthyosis, psoriasis, alopecia areata, vitiligo, and onychomycosis. The study analyzed 40 observational studies and 99 case reports, highlighting the need for improved screening and management guidelines for these conditions in the DS population. The findings suggested that patients with DS could benefit from regular dermatologic screenings to enable earlier diagnosis and treatment of these common cutaneous disorders.

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Research cited in this study

2 / 2 results

research Janus Kinase Inhibition in Down Syndrome: Two Cases of Therapeutic Benefit for Alopecia Areata

32 citations , April 2019 in “JAAD case reports”

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research Alopecia Areata in Down Syndrome: A Clinical Evaluation

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