215 citations
,
March 2011 in “Clinical Cancer Research” This study found that sorafenib was active against desmoid tumors, with 25% of patients achieving a partial response and 70% maintaining stable disease.
4 citations
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December 2024 in “JAAD Case Reports” This review discusses previously reported cases of drug-associated hidradenitis suppurativa linked to various immunomodulating medications but reports no new clinical results.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that 71% of patients treated with the gamma-secretase inhibitor PF-03084014 for desmoid tumors experienced dermatologic side effects, such as follicular lesions and pruritic eruptions, which were managed with topical or systemic treatments.
July 2025 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” In this case report, a nine-year-old boy with an unusual scalp nodule was found to have trichofolliculoma, a rare skin tumor, emphasizing the importance of considering this diagnosis in children and using dermoscopy and histopathology for accurate identification and treatment.
July 2022 in “International journal of surgery science” This case report details a rare large epidermal cyst over the sacrumcoccygeal region in an elderly patient, which was successfully removed surgically.
1 citations
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October 2023 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report describes a patient developing hidradenitis suppurativa-like lesions after undergoing gamma secretase complex inhibitor therapy for desmoid tumours, illustrating potential skin toxicity linked to the treatment.
77 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that human skin expresses proenkephalin, whose expression is upregulated by environmental stress and varies in pathological conditions, increasing in psoriasis and decreasing in melanocytic tumors.
14 citations
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January 2015 in “Hormones and Cancer” This study found that androgen receptor inactivation in male and female mice reduced susceptibility to DMBA-induced skin cancer, but the effect varied by the carcinogenesis model.
16 citations
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July 2021 in “Histopathology” This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.
This chapter classifies various benign skin tumors and discusses their characteristics, treatment indications, and potential for recurrence, but reports no new clinical findings.
3 citations
,
February 2018 in “Journal of evolution of medical and dental sciences” This study found that among patients with sex cord stromal ovarian tumors, 11% exhibited signs of virilization, requiring thorough clinical evaluation to rule out non-neoplastic causes.
February 2024 in “Journal of medical science and clinical research” This case study reports a near-complete response of a proliferating trichilemmal tumor to neoadjuvant radiotherapy in a 79-year-old woman, highlighting radiotherapy's role in managing this condition when patients are unsuitable for surgery.
March 2022 in “Folia Medica Indonesiana” This case report described a facial hairline tumor initially diagnosed as a sebaceous cyst but ultimately confirmed as a rare Proliferating Pilar Tumor with focal malignancies upon histopathological examination.
November 2011 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” This study found that Polyomavirus A2 infection in mice led to the development of pilomatricomas in hair follicles, with the virus replicating initially in the skin and later infecting matrix cells.
January 2016 in “Chemistry & Industry” This article discusses various aspects of hair loss but reports no new research findings.
2 citations
,
September 2021 in “Journal of Pathology of Nepal” This study found that cutaneous cysts most frequently appeared as epidermal cysts, with unusual locations posing diagnostic challenges that required histopathological analysis for definitive diagnosis.
7 citations
,
March 2017 in “Journal of dermatology” This review outlines the clinical and histopathological features that aid in classifying tumors arising from the folliculosebaceous apparatus and reports no new research results.
1540 citations
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October 2008 in “Fertility and Sterility” This review discusses the definition of polycystic ovary syndrome proposed by the AE-PCOS Society Task Force, emphasizing hyperandrogenism, ovarian dysfunction, and excluding related disorders, while noting potential variations needing more research.
13 citations
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June 2018 in “Dermatopathology” This classification proposal introduces a novel system for categorizing cutaneous adnexal cysts based on their origin in the folliculosebaceous unit and sweat glands, aiming to simplify and enhance understanding of these skin lesions.
2 citations
,
February 2021 in “Endocrinology, diabetes & metabolism case reports” This case report describes a 15-year-old girl with severe hyperandrogenaemia linked to both an ovarian androgen-secreting tumor and HAIR-AN syndrome, highlighting the complexity of diagnosing polycystic ovarian syndrome.
December 2021 in “International journal of research - granthaalayah” This report discusses a case of pilomatrixoma, an uncommon benign skin tumor, and emphasizes the importance of histopathological analysis for accurate diagnosis to avoid misdiagnosis as malignancy.
January 2005 in “Journal of Cutaneous Pathology” This report presents the first known case of a proliferating hybrid cyst containing both epidermoid and trichilemmal components on the scrotum of a 44-year-old man.
13 citations
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June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” This article reviews assessment and management strategies for adolescent females with excessive hair growth and highlights the importance of evaluating potential androgen sources.
2 citations
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February 2023 in “Research Square (Research Square)” In this study, a newly engineered scaffold, PADM-MX-Ag-Si@Dox, demonstrated potential as a multifunctional biomaterial for postoperative melanoma treatment by controlling drug release, enhancing wound healing, and enabling real-time tumor surveillance through temperature, pH, and electrical stimuli.
13 citations
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April 2022 in “Frontiers in oncology” This review discusses the early phases of melanomagenesis and the factors influencing melanoma cell variability and reports no new clinical results.
1 citations
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January 2022 in “Indian dermatology online journal” This case report documents the presentation and diagnosis of a rare bullous pilomatrixoma in a 20-year-old female using fine needle aspiration cytopathology, highlighting diagnostic challenges and features.
June 2024 in “Annals of Medicine and Surgery” Surgeons should know about pilomatricoma for accurate diagnosis, even though it's rare.
2 citations
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August 2023 in “Marine drugs” In this study, fish-derived collagen hydrolysate from tilapia scales improved hair growth and skin health in both cellular and mouse models, reducing oxidative stress and inflammation while enhancing hair quality and promoting beneficial gene expression.
January 2025 in “Turkiye Klinikleri Journal of Ophthalmology” This study of pilomatrixoma cases in children reveals that these benign tumors typically present as painless masses under the eyebrow and can be effectively treated with surgical excision, though rare rapid growth may occur.
1 citations
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February 2009 in “Journal of Investigative Dermatology” This study found that VEGF-deficient keratinocytes can form tumors using different aneuploidy and signaling patterns, highlighting VEGF's role beyond angiogenesis in tumor cell growth and survival.