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research Microneedles meet photomedicine: emerging strategies for diagnosis and therapy of skin diseases
This review provides an overview of microneedle-assisted photomedicine, detailing diagnostic and therapeutic strategies, design principles, and challenges for translating this approach to skin disease management.
research An open-access data set of pig skin anatomy and physiology for modelling purposes
This database provides detailed physiological parameters of porcine skin to enhance the MPML MechDermA Model, improving dermal absorption predictions for human studies in the Simcyp Simulator.
research Application of Topical Immunotherapy in the Treatment of Alopecia Areata: A Review and Update
This review summarizes the pharmacology, mechanisms, and clinical efficacy of topical immunotherapy for alopecia areata but reports no new clinical results.
research Emerging smart microneedle technologies in psoriasis: convergence of nanocarriers, machine learning, and personalized delivery
Smart microneedles using advanced tech could improve psoriasis treatment.
research Characterization of the in vitro, ex vivo, and in vivo Efficacy of the Antimicrobial Peptide DPK-060 Used for Topical Treatment
This study found that the antimicrobial peptide DPK-060 effectively reduced bacterial counts of Staphylococcus aureus and was safe for topical use in preclinical models, although nanocarrier encapsulation did not enhance its efficacy.
research Induction of Hair Follicle Regeneration in Rat Ear by Dermal Papilla Cell Microcapsules
This study found that microencapsulated dermal papillae cells induced hair follicle regeneration in rat ears, differing from normal follicles in configuration, size, number, and differentiation degree.
research Erosive pustular dermatosis of the scalp treated with 0.1% mometasone furoate cream.
In this case report, erosive pustular dermatosis of the scalp in a 49-year-old man showed improvement with daily application of 0.1% mometasone furoate cream.
research 731 Generation of a laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlas
In this study, researchers created a comprehensive transcriptome map of human hair follicle compartments, identifying compartment-specific genes and providing a resource for potential therapeutic interventions.
research Therapeutic Application of Microsponges-based Drug Delivery Systems
This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
research Fast-Embeddable Grooved Microneedles by Shear Actuation for Accurate Transdermal Drug Delivery
In this study, researchers developed grooved microneedles made from hyaluronic acid for precise transdermal drug delivery, achieving accurate dosage with a high probability of delivery (98% or more) by using an easy-to-operate applicator for shearing force.
research Modern Dermabrasion Techniques
research Enhancement of Dermal Delivery of Finasteride Using MicroemulsionSystems
This study found that finasteride microemulsions significantly increased skin permeability in vitro, highlighting the potential for enhanced delivery of this drug through the skin.
research 441 Anti-melanoma gene signature in dermal sheath fibroblasts from scalp hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB)
research Plasma Rico em Plaquetas Otimizando o Rejuvenescimento Dérmico nos Procedimentos Estéticos
This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.
research Revolutionizing psoriasis care: Microneedle innovations in treatment and diagnosis
This review highlights the application of microneedle technology as a promising advancement in psoriasis management, focusing on its roles in enhanced transdermal drug delivery and minimally invasive biomarker monitoring, while also discussing current challenges and future research directions.
research Development and optimization of finasteride-loaded microemulsions for transdermal delivery
This study found that finasteride could enhance the stemness of dermal papilla cells, suggesting potential benefits for hair regeneration approaches.
research Multidomain Peptide Hydrogel Accelerates Healing of Full-Thickness Wounds in Diabetic Mice
This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.
research Dissolving microneedle patch loading dutasteride microspheres for the long-acting treatment of androgenetic alopecia
A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.
research Re-Densification Effect of Pressure-Injected Peptide-Hyaluronic Acid Combination on Male Androgenic Alopecia
This study found that electronically-operated pneumatic injections for administering a peptide-hyaluronic acid combination were well tolerated and led to significant improvement in hair density and thickness for men with androgenic alopecia over six months, though the exact mechanism remains uncertain.
research 32571 Intensive dutasteride mesotherapy protocol (IDMP) with oral minoxidil as an alternative to antiandrogens in AGA. A retrospective analysis of a hair restoration center
In this study, the authors highlight the potential of intradermal microinjections of dutasteride as an adjunctive therapy for androgenetic alopecia, though they note that information on its effectiveness remains limited.
research CASE SERIES: TREATING HAIR LOSS WITH THE NON-INVASIVE JET PEEL TECHNOLOGY
This study evaluated the use of Jet Peel technology, a non-invasive hydroporation method, in treating androgenetic and telogen effluvium alopecia, finding improvements in hair growth and thickness, and a reduction in associated scalp conditions.
research Scalp imaging techniques
This review discusses the role of scalp imaging techniques in trichology for researching drug delivery and toxicology, without presenting new clinical results.
research Photo-responsive fibers as artificial hairs in an in-vitro model for transdermal drug delivery
This study reports the development of an artificial skin membrane incorporating hair follicles, intended as an in vitro model to better estimate drug permeation with less variability than current models used in transdermal drug delivery research.
research Reflectance confocal microscopy can differentiate dermoscopic white dots of the scalp between sweat gland ducts or follicular infundibulum
Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.
research Fractional microporation-guided delivery of nanoencapsulated drugs for enhanced cutaneous and follicular absorption: a comparison of ablative laser and radiofrequency microneedling
research Hyperdiluting Calcium Hydroxylapatite With Platelet-Rich Plasma and Hyaluronidase for Improving Neck Laxity and Wrinkle Severity
In this report, researchers observed that a single treatment using a combination of hyperdiluted calcium hydroxylapatite, platelet-rich plasma, and hyaluronidase improved neck wrinkles and skin laxity in two patients, indicating preliminary evidence for the safety and efficacy of this novel therapy.
research Intradermal and follicular delivery of adapalene liposomes
This study demonstrated that adapalene encapsulated in liposomes significantly improved drug delivery to hair follicles compared to gel and drug solution, potentially targeting acne treatment more effectively.
research Confocal Laser Scanning Microscopy: An Excellent Tool for Tracking Compounds in the Skin
This review discusses the applications of confocal laser scanning microscopy in visualizing fluorescent compounds within the skin, noting its potential for tracking drug carriers and enhancing penetration studies, but reports no new results.
research TrichoScan: A Novel Tool For The Analysis of Hair Growth In Vivo
This study reports that the TrichoScan method effectively measures hair growth parameters and detected significant improvements in hair counts and thickness in men with androgenetic alopecia after finasteride treatment.