Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that EGCG improved the integrity of skin grafts during cryopreservation, suggesting its potential usefulness for skin preservation, though the exact mechanism remains unclear.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.

In this study, using a novel topical androgen receptor suppressor, fluridil, significantly increased the percentage of growing hairs in males with androgenetic alopecia without systemic absorption or adverse side effects.

In this study, algal oligosaccharides effectively countered key factors in androgenetic alopecia pathogenesis, improving hair growth indicators in vitro and in mice.

This study reviewed competing endogenous RNA networks related to skin aging and wound healing, finding mechanisms like UVB-induced senescence and photoaging, as well as potential therapeutic targets for improving skin health and recovery.

This study found that overexpressing the gene Thymosin β4 (Tβ4) can promote the growth and development of secondary hair follicle dermal papilla cells in cashmere goats, suggesting its potential as a target for increasing cashmere production.

This review discusses the molecular mechanisms of androgen action in human hair follicles and reports no new findings; the authors emphasize the need for further research to improve treatments for hair disorders.

This review outlines the histological structures of the skin, highlighting species and regional differences in dermal absorption and obstacles encountered in toxicological assessments due to epidermal thickness variability, contact dermatitis reactions, and stem cell vulnerabilities.

In this study, photodynamic therapy was found to achieve permanent reduction of nonpigmented hair in mice, unlike an 800-nm diode laser, by targeting the hair matrix through repeated sessions.

This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.

This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.

This study revealed that during avian skin development, complex tissue architecture results from specific cellular flows and mechanical processes that guide feather bud protrusion and elongation, with distinct differences noted in scale development, where rigidity restricts such transformations.

This study observed that feeding ewes a water-soluble complex of fatty acids increased primary hair follicle bulb diameter and mitotic activity, suggesting a positive correlation with wool growth.

In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.

This review examines the potential uses of platelet-rich plasma in dermatology, noting its growing therapeutic applications, but highlights the need for more standardized procedures and larger studies to confirm its effects.

This study found that exosomes derived from human bone marrow mesenchymal stem cells significantly promote cutaneous wound healing in rats by modulating the TGF-β/Smad signaling pathway.

In this study with a rat muscle defect model, decellularized muscle matrix demonstrated better integration, neovascularization, and myogenesis compared to commercially available acellular dermal matrices, and also showed trends toward reduced inflammation and fibrosis after 30 and 60 days.

This study suggests that 4-META resin may be more effective than cyanoacrylate for promoting wound healing in rats, as the wounds were covered by epithelial tissue faster with 4-META resin.

This study found that Rubus coreanum extract promotes hair growth in mice, but its effects are not due to inhibition of specific enzymatic activities or growth factor expression.

This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.

In this study, mangosteen pericarp water extract was found to significantly promote hair dermal papilla cell proliferation and enhance melanin synthesis in vitro, surpassing known melanogenic agents such as α-melanocyte stimulating hormone and forskolin in potency.

This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.

This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.

This review discusses the role of histone deacetylases in hearing loss, proposing potential pharmacological interventions, but reports no new clinical results.

This study found that Kyoh®, a flavonol-rich extract from rocket leaves, may promote hair growth by enhancing the expression of hair growth-related genes in laboratory conditions.

The topical finasteride spray was safe and well-tolerated with stable effects.

This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.

This study found that SM04755, a novel topical drug, inhibited inflammation, keratinocyte proliferation, and fibrosis in vitro and improved skin health in a mouse model of psoriasis, indicating potential as a topical psoriasis treatment.

This study found that collagen peptides from Mozambique tilapia significantly promoted hair regrowth and increased the proliferation of hair growth factors in vitro and in vivo, suggesting potential as supplements for hair loss prevention.