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Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.

Estrogen therapy can reduce skin aging but has cancer risks.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Melatonin helps regulate hair growth and protects the hair follicle from stress.