October 2025 in “Journal of Drug Delivery Science and Technology” This study suggests that combining scalp cooling with resveratrol-loaded nanoparticles effectively protects hair follicles from chemotherapy-induced damage, highlighting a potential method to prevent hair loss during cancer treatment.
January 2024 in “Biotechnology advances” This review highlights the importance of selecting high-quality bioassays in discovering bioactive compounds from marine sources, emphasizing their role in evaluating safety and efficacy during pharmaceutical, food supplement, and cosmetic development.
5 citations
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November 2024 in “Cells” This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.
January 2026 in “Microsystems & Nanoengineering” This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.
October 2025 in “Pharmaceutics” This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.
22 citations
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June 2024 in “Cell” Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.
January 2024 in “Metabolites” This review highlights the importance of standardizing pre-analytical procedures for collecting and extracting samples from uncommon biological specimens like breast milk and sweat in clinical metabolomics, to enhance diagnostic and biomarker discovery efforts while minimizing contamination and bias.
112 citations
,
January 2004 in “The International journal of developmental biology” This study found that feather patterning is primarily self-organizing and dynamic, relying on both genetic and epigenetic controls, with implications for similar processes like fingerprints and pigmentation.
92 citations
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March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
44 citations
,
February 2023 in “Cell” In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.
30 citations
,
August 2016 in “Skin research and technology” This study used 3D imaging to reveal age-related reductions in the volumes and connectivity of dermal papillae and rete ridges at the dermal-epidermal junction, which are not fully apparent in 2D examinations.
25 citations
,
August 2024 in “Virtual and Physical Prototyping” This review outlines various 3D bioprinting techniques and bioinks used for creating artificial tissues and organs, emphasizing their potential in addressing organ transplant shortages and advancing drug testing, while acknowledging existing challenges and future prospects.
22 citations
,
April 2023 in “The Journal of Cell Biology” In this study, researchers found that coordinated intercellular Ca2+ signaling among basal stem cells in mice is crucial for cell cycle progression and tissue-wide communication during epidermal regeneration.
5 citations
,
January 2025 in “Burns & Trauma” This review highlights recent research using single-cell RNA sequencing and machine learning in wound healing, revealing significant insights into fibroblast diversity, immune cell dynamics, and the spatial organization of cells, which may transform therapeutic strategies for chronic wounds, fibrosis, and tissue regeneration.
4 citations
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October 2025 in “Science Advances” In this study, researchers found that tubular VCAM1 expression in transgenic mice and human kidney transplant biopsies precedes nephron loss and fibrosis, indicating its potential as an early biomarker for tubular fate and adverse kidney outcomes.
4 citations
,
October 2022 in “American journal of physiology. Heart and circulatory physiology” This study found that in patients with severe aortic valve stenosis, higher serum dihydrotestosterone levels were associated with increased myocardial hypertrophy, fibrosis, and reduced left ventricular function.
2 citations
,
December 2024 in “International Journal of Molecular Sciences” This study found that mesenchymal stem cells from chronically inflamed human livers maintain their key cellular characteristics, supporting their potential use in developing liver cell therapies.
August 2026 in “Cell Biomaterials” D-chiral biomaterial scaffolds enhance tissue and hair regeneration by activating the body's immune system.
June 2026 in “Nature Communications” This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.
April 2026 in “Journal of Pharmaceutical and BioTech Industry” This review highlights recent advances in personalized transdermal drug delivery systems, noting their potential for improved treatment efficacy and safety, but identifies significant challenges in clinical translation.
February 2025 in “Science Advances” This study demonstrates that Wnt signaling plays a crucial mechanoregulatory role in skin regeneration by influencing cellular responses to substrate rigidity, which promotes hair follicle regeneration in the wound-induced hair neogenesis model.
September 2024 in “Journal of Investigative Dermatology” This study developed a deep learning-based tool to quantify individual hair fibers in mice, revealing distinct hair phenotypes linked to hormonal, genetic, and age-related factors, and suggesting its potential for new diagnostic methods through hair analysis.
10 citations
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June 2022 in “Development” This study suggests that distinct chromatin topologies allow different lineage-specific enhancers to regulate Hoxd genes in mouse vibrissae and chicken feather primordia, while conserved regulatory elements maintain transcriptional robustness in the embryonic trunk across species.
8 citations
,
May 2023 in “Gels” This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.
March 2026 in “ACS Omega” This study reported that a novel hydrogel wound dressing, created using a Brachybotrys paridiformis polysaccharide derivative and chitosan, significantly accelerated wound healing and tissue regeneration in vivo, showing nearly complete healing by day 15 compared to controls.
January 2016 in “Georg Thieme Verlag eBooks” Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.
January 2020 in “Química Nova” This study used Density Functional Theory-based computational methods to analyze finasteride's molecular properties, finding that the GGA/PW91 method closely matches experimental data for vibrational frequencies and geometric parameters.
January 2021 in “Figshare” This study used Density Functional Theory to calculate finasteride's molecular properties, finding the GGA/PW91 method aligns well with experimental data and identifying key reactive sites for chemical interactions.
10 citations
,
June 1998 in “International Journal of Dermatology” This article discusses inflammatory perifollicular fibrosis and alopecia but provides no new research findings.
9 citations
,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This paper describes a systematic approach to creating a natural hairline in one session using modern hairline design principles and reports no new clinical results.