83 citations
,
August 2014 in “PLoS ONE” This study suggests that Demodex mites might universally inhabit adult humans, with a phylogenetic analysis indicating potential undiscovered lineages of the D. brevis species based on geographic differences.
81 citations
,
February 2014 in “Clinics in dermatology” This review discusses the potential role of Demodex mites in various human skin conditions, including acneiform eruptions and folliculitis, but reports no new research findings.
24 citations
,
August 2022 in “Immunity” This study found that control of Demodex mite colonization in mice required skin ILC2s and IL-13, highlighting their role in maintaining HF integrity and limiting mite overgrowth.
2 citations
,
May 2025 in “Infection” This source underscores the need for a multidisciplinary effort to raise awareness of Demodex and demodicosis, suggesting that prioritizing research, diagnostics, and treatment development could enhance global health outcomes and improve quality of life for affected individuals.
January 2024 in “Kharkiv National Medical University Repository (Kharkiv National Medical University)” This study found evidence of Demodex mite involvement in the formation of horn cysts within eyelid papillomas, suggesting a role for the mite in tumor morphogenesis.
September 2025 in “Meditsinskiy sovet = Medical Council” This review provides current insights into the role of Demodex mites in acne and rosacea, detailing their involvement in sebaceous gland diseases due to their potential to cause inflammation and disrupt skin microbial balance, while suggesting methods to correct mite overgrowth.
March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology” This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.
46 citations
,
January 1988 in “PubMed” This study found that Demodex mites may transport Microsporum canis spores on human skin, suggesting a potential role in microbial movement despite typically being considered harmless.
35 citations
,
March 1976 in “British Journal of Dermatology” This study observed no correlation between Demodex species and skin condition among Aborigines, though D. brevis was associated with sebaceous gland degeneration in one case.
36 citations
,
March 2004 in “AIDS” This case report highlights that immune reconstitution after starting HAART can lead to demodex folliculitis in HIV patients, emphasizing the need to consider it in differential diagnosis of skin eruptions.
30 citations
,
June 2013 in “Optometry and vision science” This study reports that a clinical sequence can help eye care practitioners identify Demodex mites, which are often underdiagnosed and undertreated in ocular surface diseases.
15 citations
,
March 2016 in “The American Journal of Dermatopathology” In this study, Demodex mites were infrequently found in scalp biopsies performed for hair loss, and most cases were nonpathogenic, but a minority showed folliculitis with a strong response to metronidazole therapy.
14 citations
,
March 2000 in “Journal of Zoo and Wildlife Medicine” This study identified a new Demodex species causing demodicosis in a zoo koala, successfully treated with daily oral ivermectin.
12 citations
,
April 2013 in “Clinical & experimental ophthalmology” This article does not include an abstract and reports no new clinical findings; it discusses Demodex blepharitis that mimics eyelid sebaceous gland carcinoma.
11 citations
,
June 2024 in “Clinical ophthalmology” This study highlights that Demodex mites, commonly found on human skin, can cause significant eye and skin issues such as blepharitis, rosacea, and dermatitis when present in abnormally high densities, underscoring the need for targeted management strategies.
3 citations
,
January 2019 in “Bulgarian Journal of Veterinary Medicine” This case study describes a cat co-infected with Demodex cati and feline immunodeficiency virus, showing initial treatment improvement followed by disease recurrence and eventual euthanasia.
November 2023 in “Veterinary Science and Medicine Journal” This case study describes a mixed breed dog with complex dermatitis caused by infections of Demodex sp, Sarcoptes scabiei, and Malassezia sp and reports that a combination of ivermectin treatment and sulfur shampoo improved the dog's symptoms after 14 days.
November 2025 in “Journal of arthropod-borne diseases” This study found that in a sample of 520 patients experiencing hair loss, 66.15% were infected with Demodex mites, with a significant correlation between mite density and severity of hair loss suggesting Demodex as a contributing factor.
September 2023 in “Jurnal Ilmu Kesehatan Hewan” This case report describes a Balinese breed dog diagnosed with demodecosis and malasseziosis, which improved after 30 days of treatment including amitraz, ketoconazole, and supportive therapies. The findings suggest that consistent treatment and environmental management can aid in recovery from these skin conditions in dogs.
May 2022 in “Journal of the Egyptian Society of Parasitology” This study found that Demodex folliculorum mites were detected in 1.6% of acne patients, with a higher prevalence in adolescents and those with severe acne.
15 citations
,
January 1970 in “Journal of the Bangladesh Agricultural University” This study found that 62.5% of street dogs in Dinajpur, Bangladesh, were infested with mites, with higher prevalence in younger, male, and poorer health dogs, potentially posing a public health threat.
June 2020 in “Comparative medicine” The study reported that Demodex musculi infestation was notably higher in immunodeficient mice, while infested immunocompetent mice, particularly the BALB/c strain, showed increased IgE levels and developed alopecia over time.
466 citations
,
August 2004 in “Journal of the American Academy of Dermatology” This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.
172 citations
,
December 2004 in “Journal of The American Academy of Dermatology” In this study, demodicoses were found to be relatively common among immunocompetent patients, with a notable overlap with papulopustular rosacea.
41 citations
,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the challenges and potential solutions in studying Demodex mites and their possible pathogenic role in human skin disorders but reports no new findings.
35 citations
,
February 2023 in “Journal of Clinical Medicine” This review discusses treatments for demodicosis in adults and children and provides no new clinical results; the authors emphasize the need for careful diagnosis and therapy selection.
33 citations
,
March 1996 in “Veterinary Quarterly” This report describes effective treatment of demodicosis in ferrets using amitraz, marking the first known cases in this species.
19 citations
,
April 2014 in “Veterinary Dermatology” In this case report, two cats with asthma developed localized skin lesions associated with inhalant glucocorticoid use, which resolved after adjusting treatment and administering milbemycin.
13 citations
,
October 2021 in “Anais Brasileiros de Dermatologia” This article discusses how dermoscopy, particularly "entomodermoscopy," aids in diagnosing skin infestations and infectious dermatoses, enhancing clinical evaluations, and monitoring treatment efficacy for conditions like scabies, pediculosis, myiasis, and tungiasis.
4 citations
,
January 1970 in “Bangladesh Journal of Veterinary Medicine” This study found that 88.89% of examined domestic and stray cats in Mymensingh district, Bangladesh, were infested with arthropods, notably Ctenocephalides felis felis, with higher prevalence in females and in summer for certain infections.