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Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Skin fat helps with body temperature control and has other active roles in health.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Wnt signaling is crucial for skin wound healing and reducing scars.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Skin fat plays a key role in immune defense and healing beyond just storing energy.